Martina Závorková, Vaclav Vetvicka, Josef Richter, Vlastimil Kral, Ivana Liehnova, Dobiasova L Rajnohova
{"title":"Effects of Glucan and Vitamin D Supplementation on Obesity and Lipid Metabolism in Diabetic Retinopathy.","authors":"Martina Závorková, Vaclav Vetvicka, Josef Richter, Vlastimil Kral, Ivana Liehnova, Dobiasova L Rajnohova","doi":"10.2174/1874091X01812010036","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Diabetes mellitus is a chronic disease manifested by an increase of blood glucose.</p><p><strong>Objective: </strong>To evaluate the effects of glucan and vitamin D supplementation in patients with diabetic retinopathy.</p><p><strong>Method: </strong>We evaluated the effects of 3-month supplementation with glucan and vitamin D in 54 patients with diabetic retinopathy. We measured levels of vitamin D, cholesterol, HDL cholesterol, and triglycerides.</p><p><strong>Results: </strong>The supplementation strongly decreased the cholesterol levels and improved the levels of HDL cholesterol. In addition, vitamin D levels were strongly improved, but still not at optimal values.</p><p><strong>Conclusion: </strong>From our data, we concluded that glucan and vitamin D supplementation strongly influence lipid metabolism and have positive effects on human health.</p>","PeriodicalId":38958,"journal":{"name":"Open Biochemistry Journal","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897984/pdf/","citationCount":"13","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Biochemistry Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874091X01812010036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2018/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 13
Abstract
Background: Diabetes mellitus is a chronic disease manifested by an increase of blood glucose.
Objective: To evaluate the effects of glucan and vitamin D supplementation in patients with diabetic retinopathy.
Method: We evaluated the effects of 3-month supplementation with glucan and vitamin D in 54 patients with diabetic retinopathy. We measured levels of vitamin D, cholesterol, HDL cholesterol, and triglycerides.
Results: The supplementation strongly decreased the cholesterol levels and improved the levels of HDL cholesterol. In addition, vitamin D levels were strongly improved, but still not at optimal values.
Conclusion: From our data, we concluded that glucan and vitamin D supplementation strongly influence lipid metabolism and have positive effects on human health.