[Granulomatous lymphocytic interstitial lung disease (GLILD) as a manifestation of pulmonary changes in common variable immunodeficiency (CVID) – case report].

Abstract

Common variable immunodeficiency (CVID) comprise different kinds of primary hypogammaglobulinemias of mostly unknown etiology. The onset of the disease and its clinical symptoms may appear as well in children as in adults. Apart from susceptibility to bacterial, viral and fungal infections, other clinical signs (autoimmunization, non-infectious lung and gastrointestinal diseases, neoplasm) are frequently observed. About 58% of patients with CVID develops granulomatous and lymphocytic interstitial lung disease (GLILD) associated with early mortality.