Correlation between patient perception of the ability to perform morning activities and findings on clinical examination in COPD patients in Romania.

Q4 Medicine
Pneumologia Pub Date : 2016-07-01
Florin Mihălţan, Dragos Ungureanu
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引用次数: 0

Abstract

Physical activity level is recognized as a predictor of mortality and hospitalization in patients with COPD. RELIEF (CorRELation Between PatIent PErception and Findings on Clinical Examination, NCT01627743) was a non-interventional, multicenter, prospective, 12-week study of patients aged at least 40 years with COPD stage C or D treated for at least 1 month previous enrollment with ICS/LABA combined therapy. The patients' perception on ability to perform morning activities, was evaluated with the CDLM (Capacity of Daily Living during the Morning) questionnaire.. 505 patients were included in the final analysis. The majority of patients were male (85.1%), and the mean age of study subjects was 65 years. The average duration of COPD was 5.31 years and more than half of the patients has COPD stage C (61%). The mean duration of inhaled combined therapy before study was 36 months. Hypertension was the most frequent co-morbidity reported (38.2%), followed by coronary heart disease (20.6%) The mean CDLM score increased during the prospective follow-up from 3.68 to 3.94, as well as the percentage of patients with a general health status of 4/5 from 41.2% to 57.4%. A weak-to-moderate positive correlation was found between the CDLM total score and the general health status (Kendall tau-b-values from 0.2269 to 0.3181). These results indicate a general improvement of subjective perceptions of both patients and health care providers and complete the COPD landscape research in Romania, being the firs study reporting such a correlation between patient reported outcomes and clinical assessments done by specialists.

罗马尼亚COPD患者晨间活动能力感知与临床检查结果的相关性
体力活动水平被认为是COPD患者死亡率和住院率的预测因子。RELIEF(患者感知与临床检查结果的相关性,NCT01627743)是一项非介入性、多中心、前瞻性、为期12周的研究,研究对象是年龄在40岁以上的COPD C期或D期患者,在入组前接受ICS/LABA联合治疗至少1个月。采用晨间日常生活能力(CDLM)问卷对患者晨间活动能力进行评估。505例患者纳入最终分析。患者以男性为主(85.1%),平均年龄65岁。COPD的平均病程为5.31年,超过一半的患者为COPD C期(61%)。研究前吸入联合治疗的平均持续时间为36个月。高血压是最常见的合并症(38.2%),其次是冠心病(20.6%)。在前瞻性随访期间,平均CDLM评分从3.68上升到3.94,总体健康状况为4/5的患者比例从41.2%上升到57.4%。CDLM总分与一般健康状况呈弱至中度正相关(Kendall tau-b值为0.2269 ~ 0.3181)。这些结果表明患者和卫生保健提供者的主观认知普遍改善,并完成了罗马尼亚COPD景观研究,这是第一个报告患者报告结果与专家临床评估之间相关性的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Pneumologia
Pneumologia Medicine-Pulmonary and Respiratory Medicine
CiteScore
0.20
自引率
0.00%
发文量
10
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