Marcia Christina Dornelas de Freitas, Marina Barcelos de Miranda, Daiane Teixeira de Oliveira, Sidney Augusto Vieira-Filho, Rachel Basques Caligiorne, Sonia Maria de Figueiredo
{"title":"Biological Activities of Red Propolis: A Review.","authors":"Marcia Christina Dornelas de Freitas, Marina Barcelos de Miranda, Daiane Teixeira de Oliveira, Sidney Augusto Vieira-Filho, Rachel Basques Caligiorne, Sonia Maria de Figueiredo","doi":"10.2174/1872214812666180223120316","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The red propolis (RdProp) is a resin produced by Apis mellifera bees, which collect the reddish exudate on the surface of its botanic source, the species Dalbergia ecastophyllum, popularly known in Brazil as \"rabo de bugio\". Considered as the 13th type of Brazilian propolis, this resin has been gaining prominence due to its natural composition, rich in bioactive substances not found in other types of propolis.</p><p><strong>Objective: </strong>This review aims to address the most important characteristics of RdProp, its botanical origin, the main constituents, its biological properties and the patents related to this natural product.</p><p><strong>Method: </strong>By means of the SciFinder, Google Patents, Patus® and Spacenet, scientific articles and patents involving the term \"red propolis\" were searched until August 2017.</p><p><strong>Results: </strong>A number of biological properties, including antimicrobial, anti-inflammatory, antiparasitic, antitumor, antioxidant, metabolic and nutraceutical activities are attributed to RdProp, demonstrating the great potential of its use in the food, pharmaceutical and cosmetics industries.</p><p><strong>Conclusion: </strong>The available papers are associated to pharmacological potential of RdProp, but the molecular mechanisms or bioactive compounds responsible for each activity have not yet been fully elucidat ed. The RdProp patents currently found are directed to components for the pharmaceutical industry (EP2070543A1; WO2014186851A1; FR3006589A1; CN1775277A; CN105797149A; CN1879859A), cosmetic (JP6012138B2; JP2008247830A; JP6012138B2) and food (JP5478392B2; CN101380052A; WO2006038690A1).</p>","PeriodicalId":89474,"journal":{"name":"Recent patents on endocrine, metabolic & immune drug discovery","volume":"11 1","pages":"3-12"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Recent patents on endocrine, metabolic & immune drug discovery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1872214812666180223120316","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18
Abstract
Background: The red propolis (RdProp) is a resin produced by Apis mellifera bees, which collect the reddish exudate on the surface of its botanic source, the species Dalbergia ecastophyllum, popularly known in Brazil as "rabo de bugio". Considered as the 13th type of Brazilian propolis, this resin has been gaining prominence due to its natural composition, rich in bioactive substances not found in other types of propolis.
Objective: This review aims to address the most important characteristics of RdProp, its botanical origin, the main constituents, its biological properties and the patents related to this natural product.
Method: By means of the SciFinder, Google Patents, Patus® and Spacenet, scientific articles and patents involving the term "red propolis" were searched until August 2017.
Results: A number of biological properties, including antimicrobial, anti-inflammatory, antiparasitic, antitumor, antioxidant, metabolic and nutraceutical activities are attributed to RdProp, demonstrating the great potential of its use in the food, pharmaceutical and cosmetics industries.
Conclusion: The available papers are associated to pharmacological potential of RdProp, but the molecular mechanisms or bioactive compounds responsible for each activity have not yet been fully elucidat ed. The RdProp patents currently found are directed to components for the pharmaceutical industry (EP2070543A1; WO2014186851A1; FR3006589A1; CN1775277A; CN105797149A; CN1879859A), cosmetic (JP6012138B2; JP2008247830A; JP6012138B2) and food (JP5478392B2; CN101380052A; WO2006038690A1).
背景:红色蜂胶(RdProp)是一种由蜜蜂生产的树脂，它收集其植物来源——Dalbergia ecastophyllum(在巴西俗称“rabo de bugio”)表面的红色渗出物。这种树脂被认为是第13种巴西蜂胶，由于其天然成分，富含其他蜂胶中所没有的生物活性物质，这种树脂已经获得了突出的地位。目的:综述了天然产物RdProp的主要特征、植物来源、主要成分、生物学特性及其相关专利。方法:截至2017年8月，通过SciFinder、Google Patents、Patus®和Spacenet检索涉及“红色蜂胶”一词的科学论文和专利。结果:RdProp具有抗菌、抗炎、抗寄生虫、抗肿瘤、抗氧化、代谢和营养活性等多种生物学特性，在食品、制药和化妆品行业具有巨大的应用潜力。结论:现有文献均与RdProp的药理潜力有关，但每种活性的分子机制或生物活性化合物尚未完全阐明。目前发现的RdProp专利主要针对制药行业的成分(EP2070543A1;WO2014186851A1;FR3006589A1;CN1775277A;CN105797149A;CN1879859A)，化妆品(JP6012138B2;JP2008247830A;JP6012138B2)和食品(JP5478392B2;CN101380052A;WO2006038690A1)。
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
