[Prolonged optic disc swelling in Kawasaki disease - A case report and literature review].

Yusuke Tsumura, Hiroshi Masuda, Sachiko Nishina, Tohru Kobayashi, Hiroshi Ono, Hitoshi Kato, Jun Abe, Akira Ishiguro
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引用次数: 1

Abstract

  Kawasaki disease (KD), an acute childhood panvasculitis, presents a variety of ocular complications as well as conjunctival injection among the principal symptoms. However, most pediatricians are unfamiliar with the ophthalmological complications of KD. A 2-year-old girl was referred to us from the ophthalmology department due to injected bulbar conjunctivae and optic disc swelling. She had familial exudative vitreoretinopathy as an underlying disease and the ocular findings had been made by chance while the patient was receiving an eye examination. Although she was afebrile at the time of her first medical interview, KD was diagnosed based on the presence of four of the principal symptoms including fever and dilatation of the coronary arteries. Intravenous immunoglobulin (IVIG) therapy was administered on Day 15 from the onset of fever. After IVIG administration, her laboratory test results showed rapid improvement but her optic disc swelling continued for six months. Eye complications in KD generally occur in the anterior segment, and recovery occurs within two months. Past reports have shown that in three of seven KD cases with optic disc involvement, optic disc swelling lasted over two months. This is the second case in which the condition lasted six months.

川崎病视盘肿胀延长1例并文献复习。
川崎病(Kawasaki disease, KD)是一种急性儿童全血管炎,以结膜注射为主要症状,有多种眼部并发症。然而,大多数儿科医生对KD的眼科并发症并不熟悉。一名2岁女童因球结膜注射及视盘肿胀从眼科转介至我们。她有家族性渗出性玻璃体视网膜病变作为基础疾病,眼部发现是在病人接受眼科检查时偶然发现的。虽然她在第一次就诊时发烧,但KD是根据发热和冠状动脉扩张等四种主要症状诊断的。开始发热后第15天静脉注射免疫球蛋白(IVIG)治疗。注射IVIG后,她的实验室检查结果显示迅速改善,但视盘肿胀持续了六个月。KD的眼部并发症一般发生在前段,术后2个月即可恢复。过去的报道显示,在7例KD累及视盘的病例中,有3例视盘肿胀持续超过2个月。这是第二个病情持续6个月的病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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