The Genetics of Parkinson Disease.

4区生物学 Q2 Biochemistry, Genetics and Molecular Biology

Advances in Genetics Pub Date : 2017-01-01 Epub Date: 2017-09-02 DOI:10.1016/bs.adgen.2017.08.001

Lina Mastrangelo

引用次数: 8

Abstract

The 200years of research efforts on Parkinson disease (PD) form the basis of our understanding of the second most common neurodegenerative disorder after Alzheimer disease. This journey has been marked by the revolutionary discovery of a neurotransmitter replacement therapy that provides a longer and healthier life to patients. Since 1997, the advances in the genetics of PD have expanded our understanding of this neurodegenerative disorder and they are opening up new ways to search for disease-modifying therapies. This chapter is a summary of the historical discoveries and latest progress in PD research.

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帕金森病的遗传学。

对帕金森病(PD) 200年的研究努力奠定了我们对仅次于阿尔茨海默病的第二大常见神经退行性疾病的理解基础。这段旅程的标志是一种神经递质替代疗法的革命性发现，它为患者提供了更长、更健康的生命。自1997年以来，PD遗传学的进展扩大了我们对这种神经退行性疾病的理解，并为寻找改善疾病的治疗方法开辟了新的途径。本章总结了PD研究的历史发现和最新进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in Genetics 生物-遗传学

CiteScore

5.70

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field and make this an essential series of books for anyone in the genetics field.