Ionogels: recent advances in design, material properties and emerging biomedical applications

IF 40.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Xiaotong Fan, Siqi Liu, Zhenhua Jia, J. Justin Koh, Jayven Chee Chuan Yeo, Chen-Gang Wang, Nayli Erdeanna Surat'man, Xian Jun Loh, Jean Le Bideau, Chaobin He, Zibiao Li and Teck-Peng Loh
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引用次数: 7

Abstract

Ionic liquid (IL)-based gels (ionogels) have received considerable attention due to their unique advantages in ionic conductivity and their biphasic liquid–solid phase property. In ionogels, the negligibly volatile ionic liquid is retained in the interconnected 3D pore structure. On the basis of these physical features as well as the chemical properties of well-chosen ILs, there is emerging interest in the anti-bacterial and biocompatibility aspects. In this review, the recent achievements of ionogels for biomedical applications are summarized and discussed. Following a brief introduction of the various types of ILs and their key physicochemical and biological properties, the design strategies and fabrication methods of ionogels are presented by means of different confining networks. These sophisticated ionogels with diverse functions, aimed at biomedical applications, are further classified into several active domains, including wearable strain sensors, therapeutic delivery systems, wound healing and biochemical detections. Finally, the challenges and possible strategies for the design of future ionogels by integrating materials science with a biological interface are proposed.

Abstract Image

离子凝胶:在设计、材料特性和新兴生物医学应用方面的最新进展
离子液体(IL)基凝胶(ionogels)由于其独特的离子导电性和液固两相特性而受到广泛关注。在离子凝胶中,可忽略不计的挥发性离子液体保留在相互连接的三维孔隙结构中。基于这些物理特征以及精心挑选的il的化学性质,人们对抗菌和生物相容性方面的兴趣日益浓厚。本文对近年来离子凝胶在生物医学领域的研究进展进行了综述和讨论。在简要介绍了各种类型的离子凝胶及其主要的物理化学和生物特性的基础上,提出了利用不同的围合网络制备离子凝胶的设计策略和方法。这些复杂的电离凝胶具有多种功能,旨在生物医学应用,进一步分为几个活跃的领域,包括可穿戴应变传感器,治疗递送系统,伤口愈合和生化检测。最后,提出了通过将材料科学与生物界面相结合来设计未来电离层的挑战和可能的策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Chemical Society Reviews
Chemical Society Reviews 化学-化学综合
CiteScore
80.80
自引率
1.10%
发文量
345
审稿时长
6.0 months
期刊介绍: Chemical Society Reviews is published by: Royal Society of Chemistry. Focus: Review articles on topics of current interest in chemistry; Predecessors: Quarterly Reviews, Chemical Society (1947–1971); Current title: Since 1971; Impact factor: 60.615 (2021); Themed issues: Occasional themed issues on new and emerging areas of research in the chemical sciences
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