First Reported Case of Donor Related Candida Endophthalmitis after Descemet Membrane Endothelial Keratoplasty.

IF 0.4 Q4 OPHTHALMOLOGY

Open Ophthalmology Journal Pub Date : 2017-06-19 eCollection Date: 2017-01-01 DOI:10.2174/1874364101711010117

Matthew Thompson, David Carli

引用次数: 18

Abstract

Purpose: To report the first case of Candida donor to host transmission following descemet membrane endothelial keratoplasty (DMEK) Methods: A retrospective case report. Results: A patient underwent uneventful DMEK. Following surgery the donor rim was culture positive for Candida. The patient developed fungal endophthalmitis that was treated medically with multiple injections of voriconazole and amphotericin. Medical treatment was unable to clear the infection and removal of the donor material was required. Following removal the infection subsided. Conclusion: Candida interface keratitis and endophthalmitis can occur following DMEK and may be difficult to treat medically. Early removal of the donor material should be considered.

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自体膜内皮角膜移植术后供体相关念珠菌眼内炎首例报道。

目的:报道首例假丝酵母供体向宿主传播的假丝酵母内皮角膜移植术(DMEK)。方法:回顾性病例报告。结果:1例患者顺利行DMEK。手术后供体缘念珠菌培养阳性。患者发生真菌性眼内炎，经多次注射伏立康唑和两性霉素治疗。医疗无法清除感染，因此需要移除捐赠材料。切除后感染消退。结论:DMEK术后可发生念珠菌界面角膜炎和眼内炎，药物治疗困难。应考虑尽早切除供体材料。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Ophthalmology Journal OPHTHALMOLOGY-

CiteScore

0.50

自引率

0.00%

发文量

期刊介绍： The Open Ophthalmology Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of experimental and clinical research in ophthalmology, including use of ophthalmological therapies, devices and surgical techniques. The Open Ophthalmology Journal, a peer-reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality papers rapidly and making them freely available to researchers worldwide.