Postnatal development of the circadian adrenocortical rhythm in rats with different neonatal nutrition.

Endokrinologie Pub Date : 1982-02-01

L Macho, M Ficková, V Strbák, O Földes

{"title":"Postnatal development of the circadian adrenocortical rhythm in rats with different neonatal nutrition.","authors":"L Macho, M Ficková, V Strbák, O Földes","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The development of diurnal rhythm of plasma and adrenal corticosterone levels was examined in rats overfed, standardfed and underfed during the suckling period (realised by adjustment of the number of suckling pups per litter to 4, 8, and 14). The first presence of circadian rhythm of plasma corticosterone was observed in 18-day-old overfed and standardfed rats, and slight delay in the manifestation of rhythm was noted in neonatally underfed animals (rhythm present in 21-day-old rats). The distinct circadian rhythm was present in 23- to 30-day-old rats. However in adult animals a significant diurnal rhythm of plasma and adrenal corticosterone content was noted in standardfed and underfed rats, whereas the variation of hormone levels was not significant in the neonatally overfed group. In young animals the peak of plasma corticosterone concentration occurred during the dark period while in adult animals it was shifted to the end of the light period. The values of amplitude of plasma corticosterone variation are increasing during the postnatal period. In weaned and adult rats the mesor values were found to be higher in neonatally underfed rats in comparison to the neonatally overfed group.</p>","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1982-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Endokrinologie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

The development of diurnal rhythm of plasma and adrenal corticosterone levels was examined in rats overfed, standardfed and underfed during the suckling period (realised by adjustment of the number of suckling pups per litter to 4, 8, and 14). The first presence of circadian rhythm of plasma corticosterone was observed in 18-day-old overfed and standardfed rats, and slight delay in the manifestation of rhythm was noted in neonatally underfed animals (rhythm present in 21-day-old rats). The distinct circadian rhythm was present in 23- to 30-day-old rats. However in adult animals a significant diurnal rhythm of plasma and adrenal corticosterone content was noted in standardfed and underfed rats, whereas the variation of hormone levels was not significant in the neonatally overfed group. In young animals the peak of plasma corticosterone concentration occurred during the dark period while in adult animals it was shifted to the end of the light period. The values of amplitude of plasma corticosterone variation are increasing during the postnatal period. In weaned and adult rats the mesor values were found to be higher in neonatally underfed rats in comparison to the neonatally overfed group.

本刊更多论文

不同新生儿营养对大鼠出生后肾上腺皮质昼夜节律的影响。

在哺乳期间，研究了过量喂养、标准喂养和不足喂养的大鼠血浆和肾上腺皮质酮水平的昼夜节律发展(通过将每窝哺乳幼鼠的数量调整为4、8和14只来实现)。在18日龄过量喂养和标准喂养的大鼠中首次观察到血浆皮质酮昼夜节律的存在，而在新生儿喂养不足的动物中发现节律的表现略有延迟(21日龄大鼠存在节律)。在23至30天大的大鼠中存在明显的昼夜节律。然而，在成年动物中，在标准喂养和不足喂养的大鼠中，血浆和肾上腺皮质酮含量的昼夜节律显著，而在新生儿过量喂养组中，激素水平的变化并不显著。幼龄动物血浆皮质酮浓度峰值出现在暗期，而成年动物血浆皮质酮浓度峰值出现在亮期结束时。血浆皮质酮变化幅度值在产后逐渐增加。在断奶大鼠和成年大鼠中，发现新生喂养不足的大鼠比新生喂养过量的大鼠的中脑值更高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Endokrinologie

自引率

0.00%

发文量