Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda.

IF 1.1 Q4 INFECTIOUS DISEASES
AIDS Research and Treatment Pub Date : 2017-01-01 Epub Date: 2017-04-02 DOI:10.1155/2017/3527563
Rachel Musomba, Frank Mubiru, Shadia Nakalema, Hope Mackline, Ivan Kalule, Agnes N Kiragga, Rosalind Parkes Ratanshi, Barbara Castelnuovo
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引用次数: 12

Abstract

Introduction. We aim to describe the time of entry into care and factors associated with being lost to program (LTP) in pregnant women on Option B Plus in an integrated HIV and antenatal care (ANC) clinic in Uganda. Methods. We included all pregnant women enrolled into the integrated HIV-ANC clinic from January 2012 to 31st July 2014, while the follow up period extended up to October 30th 2015. LTP was defined as being out of care for ≥3 months. Results. Overall 856 women were included. Only 36.4% (86/236) of the women were enrolled in the first trimester. Overall 69 (8.1%) were LTP. In the multivariate analysis older women (HR: 0.80 per five-year increase, CI: 0.64-1.0, and P = 0.060) and women on ART at the time of pregnancy (0.58, CI: 0.34-0.98, and P = 0.040) were more likely not to be LTP. Among women already on ART at the time of pregnancy no factor was associated with LTP. Conclusion. Our results suggest the need for interventions to enhance prompt linkage of HIV positive women to HIV services for ART initiation and for increased retention particularly in young and ART naive women.

Abstract Image

Abstract Image

描述乌干达一个大型城市中心的HIV阳性孕妇队列进入护理点和失去方案。
介绍。我们的目的是描述进入护理的时间和与失去计划(LTP)的孕妇在乌干达的一个综合艾滋病毒和产前护理(ANC)诊所选项B +的相关因素。方法。我们纳入了2012年1月至2014年7月31日在HIV-ANC综合诊所登记的所有孕妇,随访期延长至2015年10月30日。LTP定义为脱离护理≥3个月。结果。总共包括856名女性。只有36.4%(86/236)的妇女在妊娠早期登记。总共69例(8.1%)为LTP。在多变量分析中,老年妇女(HR:每5年增加0.80,CI: 0.64-1.0, P = 0.060)和怀孕时接受抗逆转录病毒治疗的妇女(HR: 0.58, CI: 0.34-0.98, P = 0.040)更有可能不发生LTP。在怀孕时已经接受抗逆转录病毒治疗的妇女中,没有任何因素与LTP相关。结论。我们的研究结果表明,需要采取干预措施,以加强艾滋病毒阳性妇女与艾滋病毒服务的迅速联系,以开始抗逆转录病毒治疗,并增加保留治疗,特别是在年轻和未接受抗逆转录病毒治疗的妇女中。
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来源期刊
AIDS Research and Treatment
AIDS Research and Treatment INFECTIOUS DISEASES-
CiteScore
3.10
自引率
0.00%
发文量
13
审稿时长
18 weeks
期刊介绍: AIDS Research and Treatment is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies focused on all aspects of HIV and AIDS, from the molecular basis of disease to translational and clinical research. In addition, articles relating to prevention, education, and behavior change will be considered
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