'Knowing what matters in diabetes: healthier below 7': results of the campaign's first 10 years (part 1): participants with known type 2 diabetes.

Cardiovascular endocrinology Pub Date : 2016-03-01 Epub Date: 2016-01-04 DOI:10.1097/XCE.0000000000000072
Stephan Jacob, Andrea Klimke-Hübner, Franz-Werner Dippel, Werner Hopfenmüller
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Abstract

Introduction: During the 'Knowing what matters in diabetes: healthier below 7' diabetes campaign, more than 30 000 randomly participating individuals underwent an occasional, voluntary diabetes risk check between 2005 and 2014.

Methods: This campaign aimed to inform individuals in Germany about diabetes mellitus and its complications, the established risk factors for development of type 2 diabetes (T2D), their prevalence and management in the real-life population, the quality of risk factor control and actual disease management in participants with a history of established diabetes mellitus [people with diabetes (PWD)]. Besides demographic characteristics (e.g. sex, age) and anamnestic information (antihypertensive treatment, history of elevated plasma glucose levels, genetic disposition), risk factor assessment included BMI, waist circumference, and lifestyle (physical activity, nutritional habits). The requested information was complemented by direct measurements of blood pressure (BP) (routine), plasma glucose, and HbA1c (voluntary). Between 2005 and 2014, more than 31 000 individuals participated in 45 single campaigns in numerous German cities. Here, we report on the results of the subgroup of participants with known diabetes mellitus.

Results: Among the 26 522 individuals with a completed questionnaire participating in the years 2006-2014, 21 055 participants (79.4%) did not have a history of diabetes and 5098 individuals (19.2%) reported being diagnosed with T2D, 369 (1.4%) with type 1 diabetes. The proportion of participants with T2D increased markedly over the years from 13.3 (2006) to 21.7% (2014). The age group older than 64 years was the largest within this subgroup (67.3%), 48.4% men and 51.6% women. The prevalence of overweight or obesity was found in 78% and 69.2% of the PWD. More than 40% of individuals with T2D had no regular physical exercise and more than 15% had unfavorable nutritional habits. In all, 69.9% of participants with T2D had elevated BP as assessed during the campaign or reported treatment with antihypertensive drugs at any time. On average, almost half of PWD (46.3%) had an HbA1c above 7.0%; a significant trend toward higher values over the 10-year period was observed.

Conclusion: The analysis of PWD participating in the 'Knowing what matters in diabetes: healthier below 7' campaign showed that despite huge efforts in the past, important aspects for progression and complications of T2D mellitus are still not well controlled. This includes lifestyle habits as well as pharmaceutical treatment. Although the participants in this study cannot be considered a representative sample of the German population and occasional measurements without standardization further limit firm conclusions, the BP, plasma glucose, and HbA1c results indicate that a major proportion of PWD have insufficient metabolic and BP control. The marked increase in the proportion of T2D among all participants over time is consistent with the increasing prevalence of T2D mellitus found in many other countries worldwide in the recent decades. Our findings underline the importance of an optimized therapy for further improvement of disease management in those already diagnosed with this common chronic, progressive disease.

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了解糖尿病中的重要因素:7 岁以下更健康":活动头 10 年的结果(第 1 部分):已知 2 型糖尿病患者。
简介2005 年至 2014 年间,在 "了解糖尿病:7 岁以下更健康 "活动期间,3 万多名随机参与者自愿接受了不定期的糖尿病风险检查:该活动旨在让德国人了解糖尿病及其并发症、2 型糖尿病(T2D)的既定发病风险因素、这些因素在现实人群中的发病率和管理、风险因素控制的质量以及有糖尿病病史的参与者(糖尿病患者 (PWD))的实际疾病管理情况。除了人口统计学特征(如性别、年龄)和异常信息(抗高血压治疗、血浆葡萄糖水平升高史、遗传倾向)外,风险因素评估还包括体重指数、腰围和生活方式(体育活动、营养习惯)。除所要求的信息外,还对血压(BP)(常规)、血浆葡萄糖和 HbA1c(自愿)进行了直接测量。2005 年至 2014 年间,超过 31 000 人参加了在德国多个城市举行的 45 次活动。在此,我们将报告已知患有糖尿病的参与者分组的结果:结果:在 2006 年至 2014 年期间,共有 26 522 人填写了调查问卷,其中 21 055 人(79.4%)没有糖尿病史,5098 人(19.2%)被诊断为 T2D,369 人(1.4%)被诊断为 1 型糖尿病。患有 T2D 的参与者比例逐年显著增加,从 13.3%(2006 年)增至 21.7%(2014 年)。在这一亚组中,64 岁以上的年龄组人数最多(67.3%),其中男性占 48.4%,女性占 51.6%。78%和69.2%的残疾人患有超重或肥胖症。超过 40% 的终末期糖尿病患者没有定期进行体育锻炼,超过 15% 的患者有不良的营养习惯。在所有患有终末期糖尿病的参与者中,69.9%的人在活动期间被评估为血压升高,或报告在任何时候接受过降压药物治疗。平均而言,近一半的残疾人(46.3%)的 HbA1c 超过 7.0%;在 10 年的时间里,观察到 HbA1c 值有明显升高的趋势:对参与 "了解糖尿病:7 岁以下更健康 "活动的残疾人进行的分析表明,尽管过去做出了巨大努力,但仍未能很好地控制 T2D 患者病情发展和并发症的重要方面。这包括生活习惯和药物治疗。虽然这项研究的参与者不能被视为德国人口的代表性样本,而且没有标准化的偶然测量也进一步限制了结论的可靠性,但血压、血浆葡萄糖和 HbA1c 的结果表明,很大一部分残疾人的代谢和血压控制不足。随着时间的推移,所有参与者中患 T2D 的比例明显增加,这与近几十年来世界上许多其他国家 T2D 患病率不断上升的趋势一致。我们的研究结果凸显了优化疗法对于进一步改善已确诊患有这种常见慢性进展性疾病的患者的疾病管理的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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