Design Approaches and Computational Tools for DNA Nanostructures

IF 1.8 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY
Heeyuen Koh;Jae Gyung Lee;Jae Young Lee;Ryan Kim;Osamu Tabata;Jin-Woo Kim;DO-Nyun Kim
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引用次数: 2

Abstract

Designing a structure in nanoscale with desired shape and properties has been enabled by structural DNA nanotechnology. Design strategies in this research field have evolved to interpret various aspects of increasingly more complex nanoscale assembly and to realize molecular-level functionality by exploring static to dynamic characteristics of the target structure. Computational tools have naturally been of significant interest as they are essential to achieve a fine control over both shape and physicochemical properties of the structure. Here, we review the basic design principles of structural DNA nanotechnology together with its computational analysis and design tools.
DNA纳米结构的设计方法和计算工具
结构DNA纳米技术使设计具有所需形状和性能的纳米级结构成为可能。该研究领域的设计策略已经发展到解释越来越复杂的纳米级组装的各个方面,并通过探索目标结构的静态到动态特性来实现分子水平的功能。计算工具自然引起了人们的极大兴趣,因为它们对于实现对结构的形状和物理化学性质的精细控制至关重要。在这里,我们回顾了结构DNA纳米技术的基本设计原则及其计算分析和设计工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.90
自引率
17.60%
发文量
10
审稿时长
12 weeks
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