Mediterranean Diet and 10-year (2002-2012) Incidence of Diabetes and Cardiovascular Disease in Participants with Prediabetes: The ATTICA study.

Q3 Medicine

Review of Diabetic Studies Pub Date : 2016-01-01 Epub Date: 2017-02-10 DOI:10.1900/RDS.2016.13.226

Theodosios D Filippatos, Demosthenes B Panagiotakos, Ekavi N Georgousopoulou, Evangelia Pitaraki, Georgia-Maria Kouli, Christina Chrysohoou, Dimitrios Tousoulis, Christodoulos Stefanadis, Christos Pitsavos

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引用次数: 35

Abstract

Background: Prediabetes has been related to an increased risk of developing diabetes and cardiovascular disease (CVD).

Aim: The aim of the present study was to examine the effect of the Mediterranean diet on diabetes and CVD risk in subjects with impaired fasting glucose (IFG, i.e. fasting plasma glucose 100-125 mg/dl).

Methods: During 2001-2002, 3042 men and women (>18y) were enrolled for the study. The participants showed no clinical evidence of CVD or any other chronic disease, and were living in the greater Athens (Greece) area. In 2011 and 2012, the 10-year follow-up examinations were performed, including a working sample of n = 1875 participants without diabetes at baseline. Adherence to the Mediterranean diet at baseline evaluation was assessed using the MedDietScore (range 0-55).

Results: The prediabetic subjects (n = 343) had a significantly higher incidence of diabetes (25% vs. 10%, p < 0.001) and CVD (17.8% vs. 12.3%, p = 0.007) compared with subjects with normal glucose values. A significant trend towards lower diabetes and CVD incidence was observed with medium and high adherence to the Mediterranean diet compared with low adherence (p < 0.001). High adherence to the Mediterranean diet (>35/55 score) was associated with lower 10-year incidence of diabetes and CVD. In multiple logistic regression models, participants with high levels of adherence to the Mediterranean diet were significantly less affected by diabetes and CVD than those with low adherence levels.

Conclusion: High adherence to the Mediterranean diet is associated with a low risk of developing diabetes and CVD in prediabetic subjects.

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地中海饮食与前驱糖尿病患者10年(2002-2012)糖尿病和心血管疾病发病率:ATTICA研究

背景:前驱糖尿病与患糖尿病和心血管疾病(CVD)的风险增加有关。目的:本研究的目的是研究地中海饮食对空腹血糖受损(IFG，即空腹血糖100-125 mg/dl)受试者糖尿病和心血管疾病风险的影响。方法:在2001-2002年期间，3042名男性和女性(>18岁)被纳入研究。参与者没有心血管疾病或任何其他慢性疾病的临床证据，并且生活在大雅典(希腊)地区。在2011年和2012年，进行了10年的随访检查，包括基线时无糖尿病的n = 1875名参与者的工作样本。基线评估时使用MedDietScore(范围0-55)评估地中海饮食的依从性。结果:糖尿病前期受试者(n = 343)的糖尿病发病率(25% vs. 10%， p < 0.001)和心血管疾病(17.8% vs. 12.3%， p = 0.007)明显高于血糖正常者。中度和高度坚持地中海饮食的患者与低坚持地中海饮食的患者相比，糖尿病和心血管疾病发病率有显著降低的趋势(p < 0.001)。高依从地中海饮食(>35/55评分)与较低的10年糖尿病和心血管疾病发病率相关。在多元logistic回归模型中，高水平坚持地中海饮食的参与者受糖尿病和心血管疾病的影响明显小于低水平坚持地中海饮食的参与者。结论:高度坚持地中海饮食与糖尿病前期受试者发生糖尿病和心血管疾病的低风险相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Review of Diabetic Studies Medicine-Internal Medicine

CiteScore

1.80

自引率

0.00%

发文量

期刊介绍： The Review of Diabetic Studies (RDS) is the society"s peer-reviewed journal published quarterly. The purpose of The RDS is to support and encourage research in biomedical diabetes-related science including areas such as endocrinology, immunology, epidemiology, genetics, cell-based research, developmental research, bioengineering and disease management.