Guillain-Barré syndrome and other neurological manifestations possibly related to Zika virus infection in municipalities from Bahia, Brazil, 2015.

Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil Pub Date : 2017-01-01 DOI:10.5123/S1679-49742017000100002

Juliane Maria Alves Siqueira Malta, Alexander Vargas, Priscila Leal E Leite, Jadher Percio, Giovanini Evelim Coelho, Andréa Helena Argolo Ferraro, Tânia Maria de Oliveira Cordeiro, Jesângeli de Sousa Dias, Eduardo Saad

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引用次数: 19

Abstract

Objective: to describe the reported cases of Guillain-Barré Syndrome (GBS) and other neurological manifestations with a history of dengue, chikungunya or Zika virus infections, in the Metropolitan Region of Salvador and in the municipality of Feira de Santana, Brazil.

Methods: this is a descriptive study with data of an investigation conducted by the epidemiological surveillance from March to August 2015; to confirm the neurological manifestations, medical diagnosis records were considered, and to prior infection, clinical and laboratory criteria were used.

Results: 138 individuals were investigated, 57 reported infectious process up to 31 days before neurological symptoms - 30 possibly due to Zika, 13 to dengue, 8 to chikungunya and 6 were inconclusive -; GBS was the most frequent neurological condition (n=46), with predominance of male sex (n=32) and the median age was 44.

Conclusion: most cases reported a clinical picture consistent with acute Zika virus disease, which preceded the occurrence of neurological symptoms.

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2015年巴西巴伊亚市可能与寨卡病毒感染有关的吉兰-巴罗综合征和其他神经系统表现。

目的:描述巴西萨尔瓦多大都市区和费拉德桑塔纳市报告的伴有登革热、基孔肯雅热或寨卡病毒感染史的吉兰-巴罗综合征(GBS)和其他神经系统症状病例。方法:采用2015年3 - 8月流行病学监测调查资料进行描述性研究;为了确认神经系统的表现，我们参考了医疗诊断记录，并使用了先前感染的临床和实验室标准。结果:对138人进行了调查，57人报告了在神经系统症状出现前31天的感染过程——30人可能是由于寨卡病毒，13人是登革热，8人是基孔肯雅热，6人尚无定论;GBS是最常见的神经系统疾病(n=46)，以男性为主(n=32)，中位年龄为44岁。结论:大多数病例报告的临床表现符合急性寨卡病毒病，在出现神经系统症状之前。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil

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