Texas Occurrence of Lyme Disease and Its Neurological Manifestations.

Journal of neuroinfectious diseases Pub Date : 2016-06-01 Epub Date: 2016-06-09 DOI:10.4172/2314-7326.1000217
Jad A Dandashi, Damir Nizamutdinov, Samantha Dayawansa, Ekokobe Fonkem, Jason H Huang
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引用次数: 4

Abstract

Today, Lyme disease is the most commonly reported tick-borne disease in the United States and Europe. The culprits behind Lyme disease are the Borrelia species of bacteria. In the USA, Borrelia burgdorferi causes the majority of cases, while in Europe and Asia Borrelia afzelii and Borrelia garinii carry the greatest burden of disease. The clinical manifestations of Lyme disease have been identified as early localized, early disseminated, and late chronic. The neurological effects of Lyme disease include both peripheral and central nervous systems involvement, including focal nerve abnormalities, cranial neuropathies, painful radiculoneuritis, meningitis, and/or toxic metabolic encephalopathy, known as Lyme encephalopathy. Given the geographic predominance of Lyme disease in the Northeast and Midwest of the USA, no major studies have been conducted regarding Southern states. Between 2005 and 2014, the Center for Disease Control has reported 582 confirmed cases of Lyme disease in Texas. Because of the potential for increased incidence and prevalence in Texas, it has become essential for research and clinical efforts to be diverted to the region. The Texas A&M College of Veterinary Medicine and Biomedical Sciences Lyme Lab has been investigating the ecology of Lyme disease in Texas and developing a pan-specific serological test for Lyme diagnosis. This report aimed to exposure materials and raise awareness of Lyme disease to healthcare providers.

德克萨斯州莱姆病的发生及其神经学表现。
今天,莱姆病是美国和欧洲最常见的蜱传疾病。莱姆病的罪魁祸首是伯氏疏螺旋体细菌。在美国,伯氏疏螺旋体引起了大多数病例,而在欧洲和亚洲,阿兹利亚疏螺旋体和加里氏疏螺旋体带来了最大的疾病负担。莱姆病的临床表现为早局限、早播散、晚慢性。莱姆病的神经系统影响包括外周和中枢神经系统受累,包括局灶性神经异常、颅神经病变、疼痛性神经根炎、脑膜炎和/或中毒性代谢性脑病,即莱姆病脑病。鉴于莱姆病在美国东北部和中西部的地理优势,尚未对南部各州进行重大研究。2005年至2014年间,美国疾病控制中心报告了德克萨斯州582例莱姆病确诊病例。由于德克萨斯州的发病率和流行率有可能增加,因此必须将研究和临床工作转移到该地区。德克萨斯农工大学兽医和生物医学科学学院莱姆病实验室一直在调查德克萨斯州莱姆病的生态学,并开发了一种用于莱姆病诊断的泛特异性血清学测试。本报告旨在向卫生保健提供者提供材料并提高对莱姆病的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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