Polychromatic Iterative Statistical Material Image Reconstruction for Photon-Counting Computed Tomography.

IF 3.3 Q2 ENGINEERING, BIOMEDICAL
International Journal of Biomedical Imaging Pub Date : 2016-01-01 Epub Date: 2016-03-17 DOI:10.1155/2016/5871604
Thomas Weidinger, Thorsten M Buzug, Thomas Flohr, Steffen Kappler, Karl Stierstorfer
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引用次数: 28

Abstract

This work proposes a dedicated statistical algorithm to perform a direct reconstruction of material-decomposed images from data acquired with photon-counting detectors (PCDs) in computed tomography. It is based on local approximations (surrogates) of the negative logarithmic Poisson probability function. Exploiting the convexity of this function allows for parallel updates of all image pixels. Parallel updates can compensate for the rather slow convergence that is intrinsic to statistical algorithms. We investigate the accuracy of the algorithm for ideal photon-counting detectors. Complementarily, we apply the algorithm to simulation data of a realistic PCD with its spectral resolution limited by K-escape, charge sharing, and pulse-pileup. For data from both an ideal and realistic PCD, the proposed algorithm is able to correct beam-hardening artifacts and quantitatively determine the material fractions of the chosen basis materials. Via regularization we were able to achieve a reduction of image noise for the realistic PCD that is up to 90% lower compared to material images form a linear, image-based material decomposition using FBP images. Additionally, we find a dependence of the algorithms convergence speed on the threshold selection within the PCD.

Abstract Image

Abstract Image

Abstract Image

光子计数计算机断层扫描的多色迭代统计材料图像重建。
本研究提出了一种专门的统计算法,用于从计算机断层扫描中使用光子计数探测器(PCDs)获得的数据中直接重建材料分解图像。它基于负对数泊松概率函数的局部近似(代理)。利用该函数的凹凸性,可以并行更新所有图像像素。并行更新可以弥补统计算法固有的缓慢收敛。我们研究了该算法在理想光子计数探测器上的准确性。此外,我们将该算法应用于具有k逃逸、电荷共享和脉冲堆积限制的光谱分辨率的实际PCD的模拟数据。对于来自理想和现实PCD的数据,所提出的算法能够纠正波束硬化伪影并定量确定所选基材料的材料组分。通过正则化,我们能够实现真实PCD图像噪声的降低,与使用FBP图像形成线性的、基于图像的材料分解的材料图像相比,噪声降低了90%。此外,我们发现算法的收敛速度依赖于PCD内阈值的选择。
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来源期刊
CiteScore
12.00
自引率
0.00%
发文量
11
审稿时长
20 weeks
期刊介绍: The International Journal of Biomedical Imaging is managed by a board of editors comprising internationally renowned active researchers. The journal is freely accessible online and also offered for purchase in print format. It employs a web-based review system to ensure swift turnaround times while maintaining high standards. In addition to regular issues, special issues are organized by guest editors. The subject areas covered include (but are not limited to): Digital radiography and tomosynthesis X-ray computed tomography (CT) Magnetic resonance imaging (MRI) Single photon emission computed tomography (SPECT) Positron emission tomography (PET) Ultrasound imaging Diffuse optical tomography, coherence, fluorescence, bioluminescence tomography, impedance tomography Neutron imaging for biomedical applications Magnetic and optical spectroscopy, and optical biopsy Optical, electron, scanning tunneling/atomic force microscopy Small animal imaging Functional, cellular, and molecular imaging Imaging assays for screening and molecular analysis Microarray image analysis and bioinformatics Emerging biomedical imaging techniques Imaging modality fusion Biomedical imaging instrumentation Biomedical image processing, pattern recognition, and analysis Biomedical image visualization, compression, transmission, and storage Imaging and modeling related to systems biology and systems biomedicine Applied mathematics, applied physics, and chemistry related to biomedical imaging Grid-enabling technology for biomedical imaging and informatics
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