PIXEL SENSIBLE LOCAL BAND ANALYSIS IN MICROSCOPIC CHROMOSOME IMAGES USING CSPA.

TSitologiia i genetika Pub Date : 2016-01-01
D Somasundaram
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Abstract

In chromosome analysis, local band analysis plays the main role to identify the perfect matched chromosome in metaspread images to attain the karyotyping. Literature investigations are narrow in chromosome image band analysis due to the higher complexities. In this paper, Pixel level based Conditional Seed Point Algorithm (CSPA) is proposed. This simulation algorithm separates the weak band region to the strong band region, and the strong band region area evaluated was based on the Region of Seed condition Points. This algorithm works well for different intensity levels and adopts the structural changes to identify the bands in image. This algorithm was simulated in more than 450 individual chromosomes to identify the local bands in the chromosome images and provided the accuracy more than 96%.

基于cspa的显微染色体图像的像素敏感局部带分析。
在染色体分析中,局部带分析主要用于识别元扩散图像中完美匹配的染色体,从而获得染色体核型。由于染色体图像波段分析的复杂性,文献研究范围较窄。提出了一种基于像素级的条件种子点算法(CSPA)。该仿真算法将弱带区域分割为强带区域,并基于种子条件点区域对强带区域进行评估。该算法可以很好地适应不同强度的图像,并利用图像的结构变化来识别图像中的波段。该算法在450多条染色体上进行了模拟,对染色体图像中的局部条带进行了识别,准确率达到96%以上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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