Ocular Surface as Barrier of Innate Immunity.

IF 0.4 Q4 OPHTHALMOLOGY

Open Ophthalmology Journal Pub Date : 2015-05-15 eCollection Date: 2015-01-01 DOI:10.2174/1874364101509010049

Rodrigo Bolaños-Jiménez, Alejandro Navas, Erika Paulina López-Lizárraga, Francesc March de Ribot, Alexandra Peña, Enrique O Graue-Hernández, Yonathan Garfias

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引用次数: 42

Abstract

Sight is one of the most important senses that human beings possess. The ocular system is a complex structure equipped with mechanisms that prevent or limit damage caused by physical, chemical, infectious and environmental factors. These mechanisms include a series of anatomical, cellular and humoral factors that have been a matter of study. The cornea is not only the most powerful and important lens of the optical system, but also, it has been involved in many other physiological and pathological processes apart from its refractive nature; the morphological and histological properties of the cornea have been thoroughly studied for the last fifty years; drawing attention in its molecular characteristics of immune response. This paper will review the anatomical and physiological aspects of the cornea, conjunctiva and lacrimal apparatus, as well as the innate immunity at the ocular surface.

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眼表作为先天免疫屏障。

视觉是人类最重要的感官之一。眼系统是一个复杂的结构，具有防止或限制物理、化学、感染和环境因素造成的损害的机制。这些机制包括一系列解剖、细胞和体液因素，这些都是研究的问题。角膜不仅是光学系统中最强大、最重要的晶状体，而且除了它的折射性质外，还参与了许多其他的生理和病理过程;近五十年来，人们对角膜的形态学和组织学特性进行了深入的研究;其免疫反应的分子特征引起人们的关注。本文将对角膜、结膜和泪器的解剖和生理方面以及眼表的先天免疫进行综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Ophthalmology Journal OPHTHALMOLOGY-

CiteScore

0.50

自引率

0.00%

发文量

期刊介绍： The Open Ophthalmology Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of experimental and clinical research in ophthalmology, including use of ophthalmological therapies, devices and surgical techniques. The Open Ophthalmology Journal, a peer-reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality papers rapidly and making them freely available to researchers worldwide.