Surgically Induced Corneal Astigmatism Following Intravitreal Ranibizumab Injection.

IF 0.4 Q4 OPHTHALMOLOGY

Open Ophthalmology Journal Pub Date : 2015-07-31 eCollection Date: 2015-01-01 DOI:10.2174/1874364101509010121

Tolga Kocatürk, Erol Erkan, Sait Eğrilmez, Harun Çakmak, Sema O Dündar, Volkan Dayanir

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引用次数: 0

Abstract

Purpose: To evaluate surgically induced astigmatism (SIA) after an intravitreal ranibizumab (IVR) injection.

Methods: Fifty eight eyes of 58 patients who underwent IVR injection due to age-related macular degeneration (wet form) or macular edema were included in this study. Patients' pre- and postoperative detailed ophthalmologic examinations were done and topographic keratometric values (K1, K2) were noted. Pre- and postoperative measurements were compared.

Results: The mean preoperative astigmatism of 0.87 Diopters (D) was found to be 0.95 D, 0.75 D, 0.82 D and 0.78 D on the 1st day, 3rd day, 1st week and 1st month, respectively. After injection, absolute change in astigmatism was found to be 0.08 D, 0.12 D, 0.05 D and 0.09 D on the 1st day, 3rd day, 1st week and 1st month, respectively. The absolute change in astigmatism seemed to be insignificant in terms of refractive analysis, however; when we performed a vectorial analysis, which takes into account changes in the axis of astigmatism, the mean value of induced astigmatism were found to be 0.33±0.22 D, 0.32±0.29 D, 0.41±0.37 D, 0.46±0.32 D on the 1st day, 3rd day, 1st week and on 1st month, respectively.

Conclusion: Intravitreal injection is a minimally invasive ophthalmologic procedure, however; it may still cause statistically significant induced astigmatism when evaluated from a vectorial point of view.

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玻璃体内注射雷尼单抗后手术性角膜散光。

目的:评估玻璃体内注射雷尼单抗(IVR)后手术性散光(SIA)。方法:58例因老年性黄斑变性(湿型)或黄斑水肿接受IVR注射的患者58只眼。对患者进行术前和术后详细的眼科检查，并记录角膜形貌测量值(K1, K2)。比较术前和术后的测量结果。结果:术前0.87屈光度(D)的平均散光在第1天、第3天、第1周和第1个月分别为0.95 D、0.75 D、0.82 D和0.78 D。注射后第1天、第3天、第1周和第1个月散光的绝对变化分别为0.08 D、0.12 D、0.05 D和0.09 D。然而，从折射分析的角度来看，散光的绝对变化似乎是微不足道的;考虑像散轴变化的矢量分析，术后第1天、第3天、第1周、第1个月的诱导像散平均值分别为0.33±0.22 D、0.32±0.29 D、0.41±0.37 D、0.46±0.32 D。结论:玻璃体内注射是一种微创眼科手术;当从矢量角度评估时，它仍然可能导致统计上显著的诱发散光。

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来源期刊

Open Ophthalmology Journal OPHTHALMOLOGY-

CiteScore

0.50

自引率

0.00%

发文量

期刊介绍： The Open Ophthalmology Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of experimental and clinical research in ophthalmology, including use of ophthalmological therapies, devices and surgical techniques. The Open Ophthalmology Journal, a peer-reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality papers rapidly and making them freely available to researchers worldwide.