Surgically Induced Corneal Astigmatism Following Intravitreal Ranibizumab Injection.

Pub Date : 2015-07-31 eCollection Date: 2015-01-01 DOI:10.2174/1874364101509010121
Tolga Kocatürk, Erol Erkan, Sait Eğrilmez, Harun Çakmak, Sema O Dündar, Volkan Dayanir
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Abstract

Purpose: To evaluate surgically induced astigmatism (SIA) after an intravitreal ranibizumab (IVR) injection.

Methods: Fifty eight eyes of 58 patients who underwent IVR injection due to age-related macular degeneration (wet form) or macular edema were included in this study. Patients' pre- and postoperative detailed ophthalmologic examinations were done and topographic keratometric values (K1, K2) were noted. Pre- and postoperative measurements were compared.

Results: The mean preoperative astigmatism of 0.87 Diopters (D) was found to be 0.95 D, 0.75 D, 0.82 D and 0.78 D on the 1st day, 3rd day, 1st week and 1st month, respectively. After injection, absolute change in astigmatism was found to be 0.08 D, 0.12 D, 0.05 D and 0.09 D on the 1st day, 3rd day, 1st week and 1st month, respectively. The absolute change in astigmatism seemed to be insignificant in terms of refractive analysis, however; when we performed a vectorial analysis, which takes into account changes in the axis of astigmatism, the mean value of induced astigmatism were found to be 0.33±0.22 D, 0.32±0.29 D, 0.41±0.37 D, 0.46±0.32 D on the 1st day, 3rd day, 1st week and on 1st month, respectively.

Conclusion: Intravitreal injection is a minimally invasive ophthalmologic procedure, however; it may still cause statistically significant induced astigmatism when evaluated from a vectorial point of view.

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玻璃体内注射雷尼单抗后手术性角膜散光。
目的:评估玻璃体内注射雷尼单抗(IVR)后手术性散光(SIA)。方法:58例因老年性黄斑变性(湿型)或黄斑水肿接受IVR注射的患者58只眼。对患者进行术前和术后详细的眼科检查,并记录角膜形貌测量值(K1, K2)。比较术前和术后的测量结果。结果:术前0.87屈光度(D)的平均散光在第1天、第3天、第1周和第1个月分别为0.95 D、0.75 D、0.82 D和0.78 D。注射后第1天、第3天、第1周和第1个月散光的绝对变化分别为0.08 D、0.12 D、0.05 D和0.09 D。然而,从折射分析的角度来看,散光的绝对变化似乎是微不足道的;考虑像散轴变化的矢量分析,术后第1天、第3天、第1周、第1个月的诱导像散平均值分别为0.33±0.22 D、0.32±0.29 D、0.41±0.37 D、0.46±0.32 D。结论:玻璃体内注射是一种微创眼科手术;当从矢量角度评估时,它仍然可能导致统计上显著的诱发散光。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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