Methicillin-Resistant Staphylococcus aureus: Treatment with Cultures of Non Drug-Resistant Staphylococcus epidermidis.

Q3 Medicine
Felix-Martin Werner, Rafael Covenas
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引用次数: 1

Abstract

The colonization and infection with methicillin-resistant Staphylococcus aureus is a major health problem in hospitals and long-term care facilities. Although bacteriaemias with MRSA (methicillin-resistant Staphylococcus aureus) can be treated with vancomycin and other reserve antibiotics, 20% of patients cannot be successfully cured. Inpatients colonized with MRSA are isolated in hospitals according to the guidelines of the Robert-Koch-Institute, although in long-term care facilities these patients are not urgently isolated. Active decolonization measures are taken to eradicate colonization with MRSA. In order to reduce MRSA colonization, it could be possible to administer cultures of Staphylococcus epidermidis which have no antibiotic resistance, so that physiological genes could be conferred from Staphylococcus epidermidis to MRSA bacteria.

耐甲氧西林金黄色葡萄球菌:非耐药表皮葡萄球菌培养治疗。
耐甲氧西林金黄色葡萄球菌的定植和感染是医院和长期护理机构的一个主要健康问题。虽然携带MRSA(耐甲氧西林金黄色葡萄球菌)的细菌血症可以用万古霉素和其他储备抗生素治疗,但20%的患者不能成功治愈。根据罗伯特-科赫研究所的指导方针,感染了MRSA的住院病人在医院被隔离,尽管在长期护理机构中,这些病人不需要紧急隔离。采取积极的去殖民化措施以根除MRSA的定植。为了减少MRSA的定植,可以使用不耐药的表皮葡萄球菌培养物,使表皮葡萄球菌的生理基因可以传递给MRSA细菌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Recent patents on anti-infective drug discovery
Recent patents on anti-infective drug discovery Medicine-Pharmacology (medical)
CiteScore
2.40
自引率
0.00%
发文量
1
期刊介绍: Recent Patents on Anti-Infective Drug Discovery publishes review articles on recent patents in the field of anti-infective drug discovery e.g. novel bioactive compounds, analogs & targets. A selection of important and recent patents on anti-infective drug discovery is also included in the journal. The journal is essential reading for all researchers involved in anti-infective drug design and discovery.
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