The effect of equisetum arvense (horse tail) ointment on wound healing and pain intensity after episiotomy: a randomized placebo-controlled trial.

IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2015-03-31 eCollection Date: 2015-03-01 DOI:10.5812/ircmj.25637
Azam Asgharikhatooni, Soheila Bani, Shirin Hasanpoor, Sakineh Mohammad Alizade, Yousef Javadzadeh
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引用次数: 31

Abstract

Background: Episiotomy, a common surgical practice in midwifery, is accompanied with high levels of pain and discomfort for mothers. The importance of medicinal herbs and traditional medicine in wound healing cannot be neglected.

Objectives: Considering the positive effects and easy accessibility of Equisetum arvense, this study examined the effectiveness of topical application of Equisetum arvense ointment in wound healing, reduction of inflammation and pain relief after episiotomy in nulliparous mothers.

Patients and methods: This double-blind clinical trial was performed on 108 postpartum nulliparous mothers (54 women in horsetail group and 54 women in placebo group) in Alzahra Educational-Medical Center (Tabriz, Iran). About 5 ± 1 and 10 ± 1 days after the childbirth, the primary outcomes of episiotomy, i.e. wound healing and pain intensity, were assessed based on redness, edema, ecchymosis, discharge and approximation of the edges (REEDA) scale and a visual analogue scale (VAS), respectively. The secondary outcomes evaluated in the current research were the number of used painkillers and the adverse events during the 10-day period of the study. Data was analyzed using independent t and Mann-Whitney U tests.

Results: The case and control groups had no significant differences in for the mean wound healing score (5.0 ± 1.6 vs. 4.1 ± 1.6) and mean pain intensity (5.7 ± 2.4 vs. 5.3 ± 2.2) at baseline. During both follow-up sessions (5 ± 1 and 10 ± 1days after delivery), the mean scores were significantly lower in the case group than the control group. The adjusted pain score difference (MD) after 5 ± 1 and 10 ± 1 days was -2.3 (95% CI: -3.2 to -1.3) and 3.8 (95% CI: -4.7 to -3.0), respectively. The mean numbers of acetaminophen pills used in the control and case groups during the 10-day period of the study were 6.8 ± 4.4 and 11.6 ± 7.1, respectively (P < 0.001).

Conclusions: According to our findings, 3% Equisetum arvense ointment promoted wound healing and relieved pain during the 10-day period after episiotomy. Since this study was the first to assess the effects of Equisetum arvense ointment on wound healing and pain intensity following episiotomy in humans, further research is warranted to fully clarify the beneficial effects of prepared ointment.

Abstract Image

马尾软膏对会阴切开术后伤口愈合和疼痛强度的影响:一项随机安慰剂对照试验。
背景:外阴切开术是助产术中一种常见的外科手术,对母亲来说伴随着高度的疼痛和不适。草药和传统医学在伤口愈合中的重要性不容忽视。目的:考虑到木犀草的积极作用和易于获取的特点,本研究考察了局部应用木犀草软膏对无产产妇会阴切开术后创面愈合、消炎和缓解疼痛的效果。患者和方法:本双盲临床试验在伊朗大不里士的Alzahra教育医疗中心对108名产后无产母亲(54名马尾组和54名安慰剂组)进行。分娩后5±1天和10±1天,分别根据红肿、水肿、瘀斑、分泌物和边缘近似(REEDA)评分和视觉模拟评分(VAS)评估会阴切开术的主要结局,即伤口愈合和疼痛强度。在本研究中评估的次要结果是在10天的研究期间使用止痛药的数量和不良事件。数据分析采用独立t检验和Mann-Whitney U检验。结果:病例组和对照组在基线时平均创面愈合评分(5.0±1.6比4.1±1.6)和平均疼痛强度(5.7±2.4比5.3±2.2)方面无显著差异。在两次随访期间(分娩后5±1天和10±1天),病例组的平均得分均显著低于对照组。5±1天和10±1天后的调整疼痛评分差(MD)分别为-2.3 (95% CI: -3.2 ~ -1.3)和3.8 (95% CI: -4.7 ~ -3.0)。对照组和病例组在10天的研究期间平均服用对乙酰氨基酚片数分别为6.8±4.4片和11.6±7.1片(P < 0.001)。结论:根据我们的研究结果,3%木犀草软膏在会阴切开术后10天内促进伤口愈合并缓解疼痛。由于这项研究首次评估了木犀草软膏对人类会阴切开术后伤口愈合和疼痛强度的影响,因此需要进一步的研究来充分阐明制备的软膏的有益作用。
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来源期刊
Iranian Red Crescent Medical Journal
Iranian Red Crescent Medical Journal 医学-医学:内科
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期刊介绍: The IRANIAN RED CRESCENT MEDICAL JOURNAL is an international, English language, peer-reviewed journal dealing with general Medicine and Surgery, Disaster Medicine and Health Policy. It is an official Journal of the Iranian Hospital Dubai and is published monthly. The Iranian Red Crescent Medical Journal aims at publishing the high quality materials, both clinical and scientific, on all aspects of Medicine and Surgery
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