Electric-Field Enhanced Molecule Detection in Suspension on Assembled Plasmonic Arrays by Raman Spectroscopy.

Chao Liu, Xiaobin Xu, D L Fan
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引用次数: 1

Abstract

One of the greatest challenges in surface enhanced Raman scattering (SERS) sensing is to detect biochemicals directly from suspension with ultrasensitivity. In this work, we employed strategically designed longitudinal nanocapsule structures with uniformly surface distributed Ag nanoparticles (Ag NPs) to dually focus and enhance SERS sensitivity of biochemicals in suspension assisted with electric fields. By tuning the reaction conditions, Ag NPs were synthesized and uniformly grown with optimized sizes and junctions on the surface of nanocapsules for well reproducible detection. The Ag NPs can further concentrate molecules from suspension due to induced electrokinetic effects in electric fields. As a result, the signals of Nile blue molecules can be enhanced by 34.4±3.1% at optimal alternating current (AC) frequencies and voltages compared to that without electric fields. This work demonstrates the dual roles of a new type of plasmonic NPs for molecule concentration and detection, which could inspire new Raman sensing devices for applications in microfluidics.

Abstract Image

Abstract Image

Abstract Image

用拉曼光谱法在组装等离子体阵列上检测悬浮液中的电场增强分子。
表面增强拉曼散射(SERS)传感的最大挑战之一是直接从悬浮液中以超灵敏度检测生物化学物质。在这项工作中,我们采用策略性设计的纵向纳米胶囊结构,表面均匀分布的银纳米粒子(Ag NPs),在电场辅助下双重聚焦并提高生物化学物质在悬浮液中的SERS敏感性。通过调整反应条件,合成并均匀生长了银纳米粒子,并优化了纳米胶囊表面的尺寸和连接,具有良好的重复性检测。由于电场诱导的电动力学效应,银纳米粒子可以进一步从悬浮液中浓缩分子。结果表明,在最佳交流电流(AC)频率和电压下,尼罗蓝分子的信号比无电场时增强了34.4±3.1%。这项工作证明了一种新型等离子体NPs在分子浓度和检测方面的双重作用,这可能会激发新的拉曼传感装置在微流体中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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