Arousal Predisposition as a Vulnerability Indicator for Psychosis: A General Population Online Stress Induction Study.

IF 3.6 Q1 PSYCHIATRY
Schizophrenia Research and Treatment Pub Date : 2015-01-01 Epub Date: 2015-06-23 DOI:10.1155/2015/725136
Annika Clamor, A Malika Warmuth, Tania M Lincoln
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引用次数: 9

Abstract

Explanatory models ascribe to arousability a central role for the development of psychotic symptoms. Thus, a disposition to hyperarousal (i.e., increased arousal predisposition (AP)) may serve as an underlying vulnerability indicator for psychosis by interacting with stressors to cause symptoms. In this case, AP, stress-response, and psychotic symptoms should be linked before the development of a diagnosable psychotic disorder. We conducted a cross-sectional online study in a population sample (N = 104; M age = 27.7 years, SD = 11.2, range 18-70). Participants rated their AP and subclinical psychotic symptoms. Participants reported their stress-levels before and after two stress inductions including an arithmetic and a social stressor. The participants with an increased AP generally felt more stressed. However, AP was not associated with the specific stress-response. As expected, positive psychotic symptoms were significantly associated with AP, but this was not mediated by general stress-levels. Its association to subtle, nonclinical psychotic symptoms supports our assumption that AP could be a vulnerability indicator for psychosis. The trait is easily accessible via a short self-report and could facilitate the identification of people at risk and be a promising target for early stress-management. Further research is needed to clarify its predictive value for stress-responses.

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唤醒易感性作为精神病的脆弱性指标:一项普通人群在线应激诱导研究。
解释模型将可唤起性归因于精神病症状发展的核心作用。因此,过度觉醒倾向(即觉醒倾向增加(AP))可能通过与压力源相互作用导致症状,作为精神病的潜在易感性指标。在这种情况下,AP、应激反应和精神病症状应该在发展为可诊断的精神病之前联系起来。我们在人口样本中进行了一项横断面在线研究(N = 104;年龄= 27.7岁,SD = 11.2,范围18-70岁)。参与者对他们的AP和亚临床精神病症状进行评分。参与者报告了他们在两次压力诱导之前和之后的压力水平,包括算术压力和社会压力。AP增加的参与者通常感到压力更大。然而,AP与特异性应激反应无关。正如预期的那样,阳性精神病症状与AP显著相关,但这不是由一般压力水平介导的。它与微妙的非临床精神病症状的关联支持了我们的假设,即AP可能是精神病的易感性指标。这一特征很容易通过简短的自我报告获得,可以帮助识别有风险的人,并成为早期压力管理的一个有希望的目标。其对应力响应的预测价值有待进一步研究。
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来源期刊
CiteScore
4.60
自引率
0.00%
发文量
2
审稿时长
14 weeks
期刊介绍: Schizophrenia Research and Treatment is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to all aspects of schizophrenia.
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