Glioblastoma, IDH-wildtype with leptomeningeal metastasis to Meckel's cave: A case report.

IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Acta radiologica open Pub Date : 2022-10-07 eCollection Date: 2022-10-01 DOI:10.1177/20584601221131480

Toshiki Murata, Masazumi Matsuda, Tetsugaku Shinozaki, Koichi Ishiyama

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引用次数: 1

Abstract

Meckel's cave or the trigeminal cistern is a subarachnoid space near the apex of the petrous portion of the temporal bone and contains cerebrospinal fluid and the Gasserian ganglion, which divides into the ophthalmic (V1), maxillary (V2), and mandibular (V3) nerves. Infectious, inflammatory, congenital, and neoplastic lesions can occur in Meckel's cave. Leptomeningeal metastasis of glioblastoma (GBM), IDH-wildtype to Meckel's cave is rare. We encountered a case of leptomeningeal metastasis of GBM to Meckel's cave in an elderly female patient who presented with pain around her right eye. Magnetic resonance imaging revealed enhancing lesions in the right temporal lobe and cervical spinal cord. The pathological diagnosis of GBM was confirmed after biopsy of the cervical spinal cord lesion, which showed hyperaccumulation of fluorodeoxyglucose (FDG) on FDG-positron emission tomography. This case indicates that metastatic lesions can also occur in Meckel's cave.

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胶质母细胞瘤，idh野生型伴脑膜轻脑膜转移至Meckel穴1例。

Meckel's cave或三叉神经池是靠近颞骨岩部顶端的蛛网膜下腔，包含脑脊液和Gasserian神经节，分为眼神经(V1)、上颌神经(V2)和下颌神经(V3)。感染性、炎性、先天性和肿瘤性病变可发生在梅克尔氏洞。胶质母细胞瘤(GBM)， idh野生型向Meckel穴转移是罕见的。我们遇到了一例GBM的脑膜转移到梅克尔洞的老年女性患者，她表现为右眼周围疼痛。磁共振成像显示右侧颞叶和颈脊髓病变增强。颈脊髓病变活检证实病理诊断为GBM, FDG-正电子发射断层扫描显示氟脱氧葡萄糖(FDG)过度积聚。这个病例表明转移性病变也可能发生在梅克尔氏洞。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Acta radiologica open

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12 weeks