Early Macular Thickness Changes after Trabeculectomy and Combined Phaco-Trabeculectomy.

IF 1.2 Q3 OPHTHALMOLOGY
Journal of Current Ophthalmology Pub Date : 2022-07-26 eCollection Date: 2022-04-01 DOI:10.4103/joco.joco_333_21
Naveed Nilforushan, Shima Loni, Parya Abdolalizadeh, Arezoo Miraftabi, Mohammad Banifatemi, Reza Rakhshan, Samira Jafari, Navid Abolfathzadeh
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引用次数: 0

Abstract

Purpose: To assess postoperative changes in central retinal thickness (RT) following trabeculectomy and combined phaco-trabeculectomy using spectral domain-optical coherence tomography.

Methods: In a prospective interventional comparative study, 64 consecutive glaucoma patients who underwent trabeculectomy (32 eyes) or phaco-trabeculectomy (32 eyes) were included. A macular thickness map using the Early Treatment Diabetic Retinopathy Study circles of 1 mm, 3 mm, and 6 mm was the standard to evaluate the 9-subfield thickness preoperatively and again at 1 and 3 months after surgery. Four subfields in each of the 3 mm and 6 mm rings were considered parafoveal and perifoveal regions, respectively.

Results: Preoperative measurements were similar in the two groups, except patients in the combined group which were older (P = 0.002). The mean RT in the combined phaco-trabeculectomy group at month 1 was significantly higher than baseline measurements at central subfield retinal thickness (CSRT) (P = 0.01), temporal (P = 0.001), and inferior (P = 0.04) parafoveal and temporal (P = 0.01), superior (P = 0.02), and nasal (P < 0.001) perifoveal quadrants; however, RT changes in the trabeculectomy-only group were not statistically significant at months 1 and 3 (P > 0.05). The increase in the temporal perifoveal RT of the combined phaco-trabeculectomy group persisted at month 3 (P = 0.01), while the RT in other sectors returned to preoperative values. The two treatment groups did not differ in terms of changes in the CSRT over time (P = 0.37). In addition, no difference was observed between the treatment groups regarding the parafoveal RTs at each time points (0.06 ≤ P ≤ 0.29).

Conclusions: There was no significant difference in the pattern of changes of CSRT and parafoveal RT between trabeculectomy and combined phaco-trabeculectomy treatment groups up to 3 months after surgery. Some detectable increase in RT in the combined phaco-trabeculectomy will reverse to baseline values 3 months after surgery, except in the temporal perifoveal region.

Abstract Image

小梁切除术和联合法氏囊-小梁切除术后早期黄斑厚度的变化
目的:使用光谱域光学相干断层扫描评估小梁切除术和超声乳化-小梁切除联合术后视网膜中央厚度(RT)的变化:在一项前瞻性介入对比研究中,共纳入了 64 名连续接受小梁切除术(32 眼)或超声乳化-小梁切除术(32 眼)的青光眼患者。黄斑厚度图以早期治疗糖尿病视网膜病变研究的 1 毫米、3 毫米和 6 毫米圈为标准,用于评估术前 9 个子野的厚度,并在术后 1 个月和 3 个月再次进行评估。3毫米和6毫米圆环内的四个子场分别被视为视网膜旁和视网膜周围区域:两组患者的术前测量结果相似,但联合组患者的年龄更大(P = 0.002)。第 1 个月时,联合手术组视网膜中央下区厚度(CSRT)(P = 0.01)、颞部(P = 0.001)和下部(P = 0.然而,单纯小梁切除术组的 RT 变化在第 1 个月和第 3 个月没有统计学意义(P > 0.05)。联合小梁切除术组的颞叶视网膜周围 RT 在第 3 个月时持续增加(P = 0.01),而其他区域的 RT 则恢复到术前值。两个治疗组的 CSRT 随时间的变化没有差异(P = 0.37)。此外,治疗组在每个时间点的视网膜旁 RT 均无差异(0.06 ≤ P ≤ 0.29):小梁切除术组和超声乳化-小梁切除术联合治疗组在术后 3 个月内的 CSRT 和视网膜旁 RT 的变化规律无明显差异。在小梁切除术和超声乳化-小梁切除术联合治疗组中,除颞叶眼底外,术后3个月RT的一些可检测到的增加会逆转到基线值。
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来源期刊
CiteScore
2.50
自引率
6.70%
发文量
45
审稿时长
8 weeks
期刊介绍: Peer Review under the responsibility of Iranian Society of Ophthalmology Journal of Current Ophthalmology, the official publication of the Iranian Society of Ophthalmology, is a peer-reviewed, open-access, scientific journal that welcomes high quality original articles related to vision science and all fields of ophthalmology. Journal of Current Ophthalmology is the continuum of Iranian Journal of Ophthalmology published since 1969.
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