Silver diamine fluoride therapy for dental care

IF 5.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review Pub Date : 2022-11-01 DOI:10.1016/j.jdsr.2022.08.001

Faith Miaomiao Zheng , Iliana Gehui Yan , Duangporn Duangthip , Sherry Shiqian Gao , Edward Chin Man Lo , Chun Hung Chu

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引用次数: 12

Abstract

Silver diamine fluoride (SDF) was developed in Japan in the 1960s. It is used to control early childhood caries, arrest root caries, prevent fissure caries and secondary caries, desensitise hypersensitive teeth, remineralise hypomineralised teeth, prevent dental erosion, detect carious tissue during excavation and manage infected root canals. SDF is commonly available as a 38% solution containing 255,000 ppm silver and 44,800 ppm fluoride ions. Silver is an antimicrobial and inhibits cariogenic biofilm. Fluoride promotes remineralisation and inhibits the demineralisation of teeth. SDF also inactivates proteolytic peptidases and inhibits dentine collagen degradation. It arrests caries without affecting dental pulp or causing dental fluorosis. Indirect pulp capping with SDF causes no or mild inflammatory pulpal response. However, direct application of SDF to dental pulp causes pulp necrosis. Furthermore, SDF stains carious lesions black. Patients must be well informed before SDF treatment. SDF therapy is simple, painless, non-invasive, inexpensive, and requires a simple armamentarium and minimal support. Both clinicians and patients generally accept it well. In 2021, the World Health Organization included SDF as an essential medicine that is effective and safe for patients. Moreover, it can be used for caries control during the COVID-19 pandemic because it is non-aerosol-generating and has a low risk of cross-infection.

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牙齿护理用氟化二胺银疗法

二胺氟化银(SDF)是20世纪60年代在日本开发的。它用于控制幼儿龋齿，抑制牙根龋齿，预防裂隙龋齿和继发性龋齿，脱敏敏感牙齿，再矿化低矿化牙齿，防止牙齿侵蚀，在挖掘过程中检测龋齿组织和处理感染的根管。SDF通常是38%的溶液，含有255,000 ppm银和44,800 ppm氟离子。银是一种抗菌和抑制龋齿的生物膜。氟化物促进牙齿再矿化，抑制牙齿脱矿。SDF还能使蛋白水解酶失活，抑制牙本质胶原降解。它可以防止蛀牙，而不会影响牙髓或引起氟斑牙。用SDF间接盖髓不会引起或轻微的牙髓炎症反应。然而，直接将SDF应用于牙髓会导致牙髓坏死。此外，SDF使龋变黑。患者在接受SDF治疗前必须充分了解情况。SDF治疗简单、无痛、无创、廉价，只需要简单的器械和最小的支持。临床医生和患者普遍接受它。2021年，世界卫生组织将SDF列为对患者有效和安全的基本药物。此外，在2019冠状病毒病大流行期间，它可用于控制龋齿，因为它不产生气溶胶，交叉感染风险低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Japanese Dental Science Review DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

9.90

自引率

1.50%

发文量

审稿时长

32 days

期刊介绍： The Japanese Dental Science Review is published by the Japanese Association for Dental Science aiming to introduce the modern aspects of the dental basic and clinical sciences in Japan, and to share and discuss the update information with foreign researchers and dentists for further development of dentistry. In principle, papers are written and submitted on the invitation of one of the Editors, although the Editors would be glad to receive suggestions. Proposals for review articles should be sent by the authors to one of the Editors by e-mail. All submitted papers are subject to the peer- refereeing process.