Determination of Five Coumarins in Angelicae Pubescentis Radix from Different Origins by HPTLC-Scanning.

IF 2.3 3区化学 Q3 CHEMISTRY, ANALYTICAL

Journal of Analytical Methods in Chemistry Pub Date : 2022-08-29 eCollection Date: 2022-01-01 DOI:10.1155/2022/3415938

Dangtong Ji, Qian Li, Hanting Yang, Yue Fan, Ting Wang, Yuying Chen

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引用次数: 2

Abstract

The HPTLC method is widely used in the field of quality evaluation and component analysis of traditional Chinese medicine (TCM). This work developed an HPTLC method to determine the five effective components of osthole, columbianadin, isoimperatorin, oxypeucedanin, and imperatorin in Angelicae Pubescentis Radix (APR) from twelve different origins, and the quality difference was analyzed by comprehensive factor analysis and cluster analysis. The results showed that the calibration curves of five components exhibited good linearity within the linear ranges (0.8-4.0 μg). The RSD of precision was 1.06%-1.21%, and the repeatability and stability tests were good. The results of cluster analysis showed that the APR from 12 different areas was divided into two categories, and at the same time, it was found that the quality of Dazhou in Sichuan and Huating in Gansu was better than in other areas. In this study, a simple, rapid, and efficient method for quality evaluation of TCM was established by the HPTLC method.

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hplc -扫描法测定不同产地当归中5种香豆素的含量。

高效液相色谱法广泛应用于中药质量评价和成分分析领域。建立了hplc法测定12种不同产地当归中蛇床子素、柱莲子苷、异欧前胡素、氧原毛苷和欧前胡素5种有效成分，并通过综合因子分析和聚类分析对其质量差异进行分析。结果表明，5种组分在0.8 ~ 4.0 μg的线性范围内具有良好的线性关系。精密度的RSD为1.06% ~ 1.21%，试验的重复性和稳定性良好。聚类分析结果表明，12个不同地区的APR可分为两类，同时发现四川达州和甘肃华亭的APR质量较好。本研究建立了一种简便、快速、高效的中药质量评价方法——高效液相色谱法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Analytical Methods in Chemistry CHEMISTRY, ANALYTICAL-ENGINEERING, CIVIL

CiteScore

4.80

自引率

3.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Journal of Analytical Methods in Chemistry publishes papers reporting methods and instrumentation for chemical analysis, and their application to real-world problems. Articles may be either practical or theoretical. Subject areas include (but are by no means limited to): Separation Spectroscopy Mass spectrometry Chromatography Analytical Sample Preparation Electrochemical analysis Hyphenated techniques Data processing As well as original research, Journal of Analytical Methods in Chemistry also publishes focused review articles that examine the state of the art, identify emerging trends, and suggest future directions for developing fields.