Relationship between refractive error and ocular biometrics in twin children: the Guangzhou Twin Eye Study.

眼科学报 Pub Date : 2014-09-01

Decai Wang, Bin Liu, Shengsong Huang, Wenyong Huang, Mingguang He

{"title":"Relationship between refractive error and ocular biometrics in twin children: the Guangzhou Twin Eye Study.","authors":"Decai Wang, Bin Liu, Shengsong Huang, Wenyong Huang, Mingguang He","doi":"","DOIUrl":null,"url":null,"abstract":"Purpose: A cross-sectional study was conducted to explore the relationship between refractive error and ocular biometrics in children from the Guangzhou twin eye study.Methods: Twin participants aged 7-15 years were selected from Guangzhou Twin Eye Study. Ocular examinations included visual acuity measurement, ocular motility evaluation, autorefraction under cycloplegia, and anterior segment, media, and fundus examination. Axial length (AL), anterior chamber depth (ACD), and corneal curvature radius were measured using partial coherence laser interferometry. A multivariate linear regression model was used for statistical analysis.Results: Twin children from Guangzhou city showed a decreased spherical equivalent with age, whereas both AL and ACD were increased and corneal curvature radius remained unchanged. When adjusted by age and gender, the data from 77% of twins presenting with spherical equivalent changes indicated that these were caused by predictable variables (R2 = 0.77, P < 0.001). Primary factors affecting children's refraction included axial length (β = -0.97,P < 0.001), ACD (β = 0.33, P < 0.001), and curvature radius (β = 2.10, P < 0.001). Girls had a higher tendency for myopic status than did boys (β = -0.26, P < 0.001). Age exerted no effect upon the changes in refraction (β = -0.01, P = 0.25).Conclusion: Refraction is correlated with ocular biometrics. Refractive status is largely determined by axial length as the major factor.","PeriodicalId":12096,"journal":{"name":"眼科学报","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"眼科学报","FirstCategoryId":"3","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: A cross-sectional study was conducted to explore the relationship between refractive error and ocular biometrics in children from the Guangzhou twin eye study.

Methods: Twin participants aged 7-15 years were selected from Guangzhou Twin Eye Study. Ocular examinations included visual acuity measurement, ocular motility evaluation, autorefraction under cycloplegia, and anterior segment, media, and fundus examination. Axial length (AL), anterior chamber depth (ACD), and corneal curvature radius were measured using partial coherence laser interferometry. A multivariate linear regression model was used for statistical analysis.

Results: Twin children from Guangzhou city showed a decreased spherical equivalent with age, whereas both AL and ACD were increased and corneal curvature radius remained unchanged. When adjusted by age and gender, the data from 77% of twins presenting with spherical equivalent changes indicated that these were caused by predictable variables (R2 = 0.77, P < 0.001). Primary factors affecting children's refraction included axial length (β = -0.97,P < 0.001), ACD (β = 0.33, P < 0.001), and curvature radius (β = 2.10, P < 0.001). Girls had a higher tendency for myopic status than did boys (β = -0.26, P < 0.001). Age exerted no effect upon the changes in refraction (β = -0.01, P = 0.25).

Conclusion: Refraction is correlated with ocular biometrics. Refractive status is largely determined by axial length as the major factor.

本刊更多论文

屈光不正与双胞胎儿童眼部生物特征的关系:广州双胞胎眼研究。

目的:通过横断面研究探讨广州双眼研究中儿童屈光不正与眼部生物特征的关系。方法:从广州双胞胎眼研究中选取7 ~ 15岁的双胞胎受试者。眼部检查包括视力测量、眼球运动评估、睫状体麻痹后的自体屈光、前节、中膜和眼底检查。采用部分相干激光干涉测量角膜轴长(AL)、前房深度(ACD)和角膜曲率半径。采用多元线性回归模型进行统计分析。结果:广州市双胞胎儿童随年龄增长，角膜球形当量降低，AL和ACD均增加，角膜曲率半径保持不变。当根据年龄和性别进行调整时，来自77%的双胞胎的数据显示球形等效变化是由可预测的变量引起的(R2 = 0.77, P < 0.001)。影响儿童屈光的主要因素包括眼轴长度(β = -0.97,P < 0.001)、ACD (β = 0.33, P < 0.001)和曲率半径(β = 2.10, P < 0.001)。女生近视倾向高于男生(β = -0.26, P < 0.001)。年龄对屈光度变化无明显影响(β = -0.01, P = 0.25)。结论:屈光与眼部生物特征相关。折射状态在很大程度上是由轴向长度作为主要因素决定的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

眼科学报

自引率

0.00%

发文量

1312

期刊介绍： Eye science was founded in 1985. It is a national medical journal supervised by the Ministry of Education of the People's Republic of China, sponsored by Sun Yat-sen University, and hosted by Sun Yat-sen University Zhongshan Eye Center (in October 2020, it was changed from a quarterly to a monthly, with the publication number: ISSN: 1000-4432; CN: 44-1119/R). It is edited by Ge Jian, former dean of Sun Yat-sen University Zhongshan Eye Center, Liu Yizhi, director and dean of Sun Yat-sen University Zhongshan Eye Center, and Lin Haotian, deputy director of Sun Yat-sen University Zhongshan Eye Center, as executive editor. It mainly reports on new developments and trends in the field of ophthalmology at home and abroad, focusing on basic research in ophthalmology, clinical experience, and theoretical knowledge and technical operations related to epidemiology. It has been included in important databases at home and abroad, such as Chemical Abstract (CA), China Journal Full-text Database (CNKI), China Core Journals (Selection) Database (Wanfang), and Chinese Science and Technology Journal Database (VIP).