Peritoneal carcinomatosis: intraoperative parameters in open (coliseum) versus closed abdomen HIPEC.

IF 1.6 Q4 ONCOLOGY
International Journal of Surgical Oncology Pub Date : 2015-01-01 Epub Date: 2015-02-15 DOI:10.1155/2015/610597
E Halkia, A Tsochrinis, D T Vassiliadou, A Pavlakou, A Vaxevanidou, A Datsis, E Efstathiou, J Spiliotis
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引用次数: 39

Abstract

Background: Peritoneal carcinomatosis (PC) is associated with a poor prognosis. Cytoreductive surgery (CRS) and HIPEC play an important role in well-selected patients with PC. The aim of the study is to present the differences in the intraoperative parameters in patients who received HIPEC in two different manners, open versus closed abdomen.

Patients and methods: The population includes 105 patients with peritoneal carcinomatosis from colorectal, gastric, and ovarian cancer, sarcoma, mesothelioma, and pseudomyxoma peritonei. Group A (n = 60) received HIPEC using the open technique and Group B (n = 45) received HIPEC with the closed technique. The main end points were morbidity, mortality, and overall hospital stay.

Results: There were two postoperative deaths (3.3%) in the open group versus no deaths in the closed group. Twenty-two patients in the open group (55%) had grade III-IV complications versus 18 patients in the closed group (40%). There are more stable intraoperative conditions in the closed abdomen HIPEC in CVP, pulse rate, and systolic pressure parameters.

Conclusions: Both methods are equal in the HIPEC procedures. Perhaps the closed method is the method of choice for frail patients due to more stable hemodynamic parameters.

Abstract Image

Abstract Image

腹膜癌:术中参数在开放(竞技场)与封闭腹部HIPEC。
背景:腹膜癌(PC)预后不良。细胞减少手术(CRS)和HIPEC在精心挑选的PC患者中发挥重要作用。本研究的目的是介绍两种不同方式(开腹和闭腹)HIPEC患者术中参数的差异。患者和方法:人群包括105例来自结直肠癌、胃癌、卵巢癌、肉瘤、间皮瘤和腹膜假性黏液瘤的腹膜癌。A组(n = 60)采用开放式技术进行HIPEC, B组(n = 45)采用封闭式技术进行HIPEC。主要终点是发病率、死亡率和总住院时间。结果:开放组术后死亡2例(3.3%),封闭组无死亡。开放组22例(55%)出现III-IV级并发症,而封闭组18例(40%)。闭腹HIPEC术中CVP、脉搏率和收缩压参数更为稳定。结论:两种方法在HIPEC手术中是相同的。由于血流动力学参数更稳定,封闭方法可能是体弱患者的首选方法。
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来源期刊
CiteScore
3.70
自引率
0.00%
发文量
5
审稿时长
20 weeks
期刊介绍: International Journal of Surgical Oncology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of surgical oncology.
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