Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy.

Sathish Manthena, Amitha Ramesh, Adusumilli Srikanth, M V Ramoji Rao, P Lakshmi Preethi, Y Pallavi Samatha
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Abstract

Context: Antimicrobial efficacy of subgingival chlorhexidine (CHX) application using two different vehicles of delivery.

Aims: The aim was to evaluate the efficacy of CHX varnish and gel as an adjunct to scaling and root planing (SRP) in reducing microbial count within moderate to deep periodontal pockets.

Settings and design: Experimental parallel mouth study.

Subjects and methods: A total of 30 subjects between the age groups 25 and 55 years having moderate to severe periodontitis, with pocket depth ≥ 5 mm were selected for the study. The selected patients were randomized into three groups of 10 each. Subjects in Group 1 received SRP followed by subgingival application of CHX varnish, subjects in Group 2 received SRP followed by subgingival application of CHX gel, subjects in Group 3 received SRP alone. Subgingival plaque samples were collected to estimate mean motile and nonmotile microbial counts using dark field microscopy at baseline, 1 week, 1 month, and 3 months.

Results: After 3 months, there was statistically significant reduction in nonmotile microbial count in all the three groups. Motile microbial count was significantly reduced in all the three groups till 1 month from baseline. Only subjects in Group 1 who received subgingival CHXvarnish after SRP showed a significant reduction in motile microbial count till 3 months from baseline.

Conclusions: Subgingival application of highly concentrated CHX varnish following SRP is beneficial in reducing microbial count in moderate to deep periodontal pockets.

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龈下给药洗必泰清漆和洗必泰凝胶在机械牙周治疗后减少微生物数量方面的比较评估。
背景:使用两种不同给药载体进行龈下洗必泰(CHX)应用的抗菌效果。目的:旨在评估CHX清漆和凝胶作为洗牙和根面平整(SRP)的辅助手段在减少中度至深度牙周袋内微生物数量方面的效果:实验性平行口腔研究:研究共选择了 30 名年龄介于 25 岁至 55 岁之间、患有中度至重度牙周炎且牙周袋深度≥ 5 毫米的患者。被选中的患者被随机分为三组,每组 10 人。第 1 组患者在接受 SRP 治疗的同时龈下涂抹 CHX 光油;第 2 组患者在接受 SRP 治疗的同时龈下涂抹 CHX 凝胶;第 3 组患者仅接受 SRP 治疗。在基线、1周、1个月和3个月时,收集龈下牙菌斑样本,使用暗视野显微镜估算活动和非活动微生物的平均数量:3 个月后,所有三组的非活动微生物数量均有显著减少。从基线开始到 1 个月前,所有三组的可动微生物数量都明显减少。只有在 SRP 后接受龈下 CHXvarnish 的第 1 组受试者的活动微生物数量在自基线算起的 3 个月内有明显减少:结论:SRP 后在龈下涂抹高浓度 CHX 光油有利于减少中度至深度牙周袋中的微生物数量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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