Multimorbidity disease clusters in Aboriginal and non-Aboriginal Caucasian populations in Canada.

J P Kuwornu, L M Lix, S Shooshtari
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Abstract

Introduction: Patterns of multimorbidity, the co-occurrence of two or more chronic diseases, may not be constant across populations. Our study objectives were to compare prevalence estimates of multimorbidity in the Aboriginal population in Canada and a matched non-Aboriginal Caucasian population and identify the chronic diseases that cluster in these groups.

Methods: We used data from the 2005 Canadian Community Health Survey (CCHS) to identify adult (≥ 18 years) respondents who self-identified as Aboriginal or non-Aboriginal Caucasian origin and reported having 2 or more of the 15 most prevalent chronic conditions measured in the CCHS. Aboriginal respondents who met these criteria were matched on sex and age to non-Aboriginal Caucasian respondents. Analyses were stratified by age (18-54 years and ≥ 55 years). Prevalence was estimated using survey weights. Latent class analysis (LCA) was used to identify disease clusters.

Results: A total of 1642 Aboriginal respondents were matched to the same number of non-Aboriginal Caucasian respondents. Overall, 38.9% (95% CI: 36.5%-41.3%) of Aboriginal respondents had two or more chronic conditions compared to 30.7% (95% CI: 28.9%-32.6%) of non-Aboriginal respondents. Comparisons of LCA results revealed that three or four clusters provided the best fit to the data. There were similarities in the diseases that tended to co-occur amongst older groups in both populations, but differences existed between the populations amongst the younger groups.

Conclusion: We found a small group of younger Aboriginal respondents who had complex co-occurring chronic diseases; these individuals may especially benefit from disease management programs.

加拿大土著和非土著白种人人群的多发病群。
多病模式,即两种或两种以上慢性病的同时发生,在人群中可能不是恒定的。我们的研究目的是比较加拿大土著人口和匹配的非土著高加索人口中多病的患病率估计,并确定这些群体中聚集的慢性疾病。方法:我们使用2005年加拿大社区健康调查(CCHS)的数据来确定自认为是土著或非土著高加索人的成年(≥18岁)受访者,并报告患有CCHS中测量的15种最常见慢性病中的2种或更多。符合这些标准的原住民受访者在性别和年龄上与非原住民白种人受访者相匹配。分析按年龄分层(18-54岁和≥55岁)。使用调查权重估计患病率。潜在类分析(LCA)用于识别疾病聚集。结果:共有1642名原住民受访者与相同数量的非原住民白种人受访者相匹配。总体而言,38.9% (95% CI: 36.5%-41.3%)的土著受访者患有两种或两种以上的慢性疾病,而非土著受访者为30.7% (95% CI: 28.9%-32.6%)。LCA结果的比较表明,三个或四个聚类提供了最佳的拟合数据。在两种人群中,老年人群往往同时发生的疾病有相似之处,但在年轻人群中,人群之间存在差异。结论:我们发现一小群年轻的原住民受访者患有复杂的并发慢性疾病;这些人可能特别受益于疾病管理计划。
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来源期刊
Chronic Diseases and Injuries in Canada
Chronic Diseases and Injuries in Canada PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-MEDICINE, GENERAL & INTERNAL
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