{"title":"Wnt signaling in C. elegans.","authors":"Hitoshi Sawa, Hendrik C Korswagen","doi":"10.1895/wormbook.1.7.2","DOIUrl":null,"url":null,"abstract":"<p><p>Wnt proteins are secreted lipid-modified glycoproteins that control many aspects of development in organisms ranging from sponges to vertebrates. Wnt proteins are also important regulators of C. elegans development, with functions in processes as diverse as cell fate specification, asymmetric cell division, cell migration and synapse formation. In this review, we will give an overview of what we currently know about the signaling mechanisms that mediate these different functions of Wnt. </p>","PeriodicalId":75344,"journal":{"name":"WormBook : the online review of C. elegans biology","volume":" ","pages":"1-30"},"PeriodicalIF":0.0000,"publicationDate":"2013-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402212/pdf/","citationCount":"96","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"WormBook : the online review of C. elegans biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1895/wormbook.1.7.2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 96
Abstract
Wnt proteins are secreted lipid-modified glycoproteins that control many aspects of development in organisms ranging from sponges to vertebrates. Wnt proteins are also important regulators of C. elegans development, with functions in processes as diverse as cell fate specification, asymmetric cell division, cell migration and synapse formation. In this review, we will give an overview of what we currently know about the signaling mechanisms that mediate these different functions of Wnt.
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