{"title":"Photonic crystal fibre for blood components sensing","authors":"Abdul Mu'iz Maidi , Md. Abul Kalam , Feroza Begum","doi":"10.1016/j.sbsr.2023.100565","DOIUrl":null,"url":null,"abstract":"<div><p>A photonic crystal fibre (PCF)-based sensor has been proposed and thoroughly investigated for the identification of blood components, including red blood cells, haemoglobin, white blood cells, plasma, and water. To evaluate the sensor's sensing and propagation properties, a numerical analysis was performed using the COMSOL Multiphysics software. The proposed sensor design features an octagonal core and two layers of cladding with octagonal and circular air holes. At the optimal wavelength of 7.0 μm, the extensive simulation results confirms that the proposed sensor achieves high relative sensitivity of 99.89%, 99.13%, 97.95%, 97.77%, and 96.68% for red blood cells, haemoglobin, white blood cells, plasma, and water, respectively. Furthermore, the design demonstrates favourable confinement loss, propagation constant, V-parameter, spot size, and beam divergence. Therefore, the proposed PCF-based sensor holds great promise not only for medical sensing applications but also for optical communications. Its advanced design and highly sensitive capabilities make it a valuable tool for a wide range of potential applications in the biomedical and telecommunications fields.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"41 ","pages":"Article 100565"},"PeriodicalIF":5.4000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sensing and Bio-Sensing Research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S221418042300017X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 2
Abstract
A photonic crystal fibre (PCF)-based sensor has been proposed and thoroughly investigated for the identification of blood components, including red blood cells, haemoglobin, white blood cells, plasma, and water. To evaluate the sensor's sensing and propagation properties, a numerical analysis was performed using the COMSOL Multiphysics software. The proposed sensor design features an octagonal core and two layers of cladding with octagonal and circular air holes. At the optimal wavelength of 7.0 μm, the extensive simulation results confirms that the proposed sensor achieves high relative sensitivity of 99.89%, 99.13%, 97.95%, 97.77%, and 96.68% for red blood cells, haemoglobin, white blood cells, plasma, and water, respectively. Furthermore, the design demonstrates favourable confinement loss, propagation constant, V-parameter, spot size, and beam divergence. Therefore, the proposed PCF-based sensor holds great promise not only for medical sensing applications but also for optical communications. Its advanced design and highly sensitive capabilities make it a valuable tool for a wide range of potential applications in the biomedical and telecommunications fields.
期刊介绍:
Sensing and Bio-Sensing Research is an open access journal dedicated to the research, design, development, and application of bio-sensing and sensing technologies. The editors will accept research papers, reviews, field trials, and validation studies that are of significant relevance. These submissions should describe new concepts, enhance understanding of the field, or offer insights into the practical application, manufacturing, and commercialization of bio-sensing and sensing technologies.
The journal covers a wide range of topics, including sensing principles and mechanisms, new materials development for transducers and recognition components, fabrication technology, and various types of sensors such as optical, electrochemical, mass-sensitive, gas, biosensors, and more. It also includes environmental, process control, and biomedical applications, signal processing, chemometrics, optoelectronic, mechanical, thermal, and magnetic sensors, as well as interface electronics. Additionally, it covers sensor systems and applications, µTAS (Micro Total Analysis Systems), development of solid-state devices for transducing physical signals, and analytical devices incorporating biological materials.