An unusual case of pulmonary mucous gland adenoma with fibromyxoid stroma and cartilage islands in 68-year-old woman.

Abstract

Pulmonary mucous gland adenoma (MGA) is an uncommon, benign tumor that histologically resembles the mucus-secreting component of the tracheobronchial gland. The majority of such tumors arise within the main, lobar or segmental bronchi, but peripheral lesions have been reported.1 The exact incidence rate cannot be determined, but its rarity can be presumed considering that the ten cases reported by England and Hochholzer2 is the largest available data set. Four cases of MGA were reported in Korea,1,3 and our case is the second presenting in the peripheral lung.1 MGA comprises many mucin-filled cystic spaces lined by bland columnar or flattened mucus-secreting cells. Though MGA usually has bands of spindle-rich stroma and may be hyalinized, multiple cartilage islands are an extraordinary finding. To the best of our knowledge, there has been no case of MGA combined with hamartoma-like stroma. Herein, we report a case of bronchial MGA with fibromyxoid stroma and cartilage islands in a 68-year-old woman.