Late metastasis from renal cell carcinoma to the thyroid and nasal cavity: report of a case.

A Roux, A M Alzharani, C Rousselot, P Beutter, D Bakhos
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Abstract

Multifocal cervico-facial metastases are very rare. Medical history of the patient and clinical context make easier the diagnosis. A 54-year-old woman presenting with a nasal obstruction, was referred to our department. She had a past medical history of an operated renal cancer 12 years ago and a right hemithyroidectomy 30 years ago. Clinical examination revealed a polypoid lesion obstructing the right nasal cavity and a thyroid goiter. Fine-needle aspiration was positive for a renal metastasis. Computed tomography confirmed the nasal lesion without bone destruction and a cervical cystic lesion into the left thyroid lobe. Completion thyroidectomy and polyp excision were performed. The final histologic examination revealed a metastasis from a renal cancer. The association of intra-thyroid and nasal cavity metastases is uncommon and not related in the literature, the practitioner must suspect the diagnosis if the patient had a thyroid tumor, a suspicious nasal lesion and a past history of cancer. The surgical management is recommended for isolated metastasis to the nasal cavity and the thyroid gland especially in renal cancer.

肾细胞癌晚期转移至甲状腺及鼻腔1例。
多灶性颈部-面部转移非常罕见。患者的病史和临床情况使诊断更容易。一位54岁的女性因鼻塞被转介到我科。12年前曾做过肾癌手术,30年前做过右甲状腺切除术。临床检查发现息肉样病变阻塞右鼻腔和甲状腺肿。细针穿刺肾转移阳性。计算机断层扫描证实鼻病变无骨破坏和宫颈囊性病变进入左甲状腺叶。完成甲状腺切除术和息肉切除术。最后的组织学检查显示为肾癌转移。甲状腺内和鼻腔转移的关联并不常见,在文献中也没有相关的文献,如果患者有甲状腺肿瘤、可疑的鼻腔病变和既往的癌症病史,医生必须怀疑诊断。对于孤立性鼻腔和甲状腺转移,尤其是肾癌,建议采用手术治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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