Punctal plugs versus artificial tears for treating dry eye: a comparative observation of their effects on contrast sensitivity.

Journal of ocular biology, diseases, and informatics Pub Date : 2012-11-29 eCollection Date: 2012-01-01 DOI:10.1007/s12177-012-9094-x
Weiqiang Qiu, Ziyuan Liu, Zhihong Zhang, Mingxin Ao, Xuemin Li, Wei Wang
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引用次数: 11

Abstract

This study aimed to compare the effects of treatment with punctal plugs versus artificial tears on visual function and tear film stability for dry eye. A total of 56 consecutive eyes of 28 dry eye patients observed at our clinic from May to October in 2009 were divided into two groups. One group (32 eyes of 16 patients) was treated with artificial tears, and punctal plugs were used in the other group (24 eyes of 12 patients). A questionnaire was used in these patients before treatment and was repeated 2 weeks after treatment. Fluorescent staining for tear film break-up time (BUT), the Schirmer test I (STI), and contrast sensitivity was performed at the same time. The questionnaire indicated that all patients complained about the uncomfortable symptoms associated with dry eye. These symptoms were relieved after the application of artificial tears or punctal plugs, and there was no significant difference between these two groups. We found that the corneal fluorescent staining disappeared after treatment. The BUT was improved significantly after treatment in both groups, but the improvement was greater in patients who received punctal plugs than those that received artificial tears. There was no remarkable change in the STI in the artificial tears group, but a significant change was observed in the punctal plugs group. The contrast sensitivities were greatly improved in simulated daylight, night, and glare disability conditions after treatment with artificial tears and punctal plugs. However, the changes in contrast sensitivity did not significantly differ between groups. Both artificial tears and punctal plugs relieved dry eye symptoms, repaired corneal lesions, enhanced tear film stability, and improved contrast sensitivity. Punctal plugs could improve tear film stability and elongate the BUT better than artificial tears.

点塞与人工泪液治疗干眼症:对比敏感度的比较观察。
本研究旨在比较点栓治疗与人工泪液治疗对干眼症患者视觉功能和泪膜稳定性的影响。将2009年5月至10月在我诊所连续观察的28例干眼症患者56只眼分为两组。一组(16例32眼)采用人工泪液治疗,另一组(12例24眼)采用点状眼塞治疗。在治疗前和治疗后2周对这些患者进行问卷调查。同时进行泪膜破裂时间(BUT)、Schirmer试验I (STI)和对比灵敏度的荧光染色。调查问卷显示,所有患者都抱怨干眼症相关的不适症状。应用人工泪液或点塞后,上述症状均有所缓解,两组间差异无统计学意义。我们发现治疗后角膜荧光染色消失。治疗后,两组患者的BUT均有显著改善,但接受点塞治疗的患者比接受人工泪液治疗的患者改善更大。人工泪液组STI无显著变化,而点塞组STI有显著变化。在人工泪液和点状眼塞治疗后,在模拟日光、夜间和眩光残疾条件下,对比灵敏度大大提高。然而,对比敏感度的变化在两组之间没有显著差异。人工泪液和点塞均可缓解干眼症状,修复角膜病变,增强泪膜稳定性,提高对比敏感度。与人工泪液相比,点塞能提高泪膜的稳定性,延长泪膜的长度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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