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{"title":"Oxygen-releasing biomaterials for tissue engineering","authors":"Gulden Camci-Unal, Neslihan Alemdar, Nasim Annabi, Ali Khademhosseini","doi":"10.1002/pi.4502","DOIUrl":null,"url":null,"abstract":"<p><b>Due to the increasing demand to generate thick and vascularized tissue-engineered constructs, novel strategies are currently being developed. An emerging example is the generation of oxygen-releasing biomaterials to tackle mass transport and diffusion limitations within engineered tissue constructs. Biomaterials containing oxygen-releasing molecules can be fabricated in various forms, such as hybrid thin films, microparticles or three dimensional scaffolds. In this perspective, we summarize various oxygen-releasing reagents and their potential applications in regenerative engineering. Moreover, we review the main approaches for fabricating oxygen-releasing biomaterials for a range of tissue engineering applications. © 2013 Society of Chemical Industry</b></p>","PeriodicalId":20404,"journal":{"name":"Polymer International","volume":"62 6","pages":"843-848"},"PeriodicalIF":2.9000,"publicationDate":"2013-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pi.4502","citationCount":"122","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polymer International","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pi.4502","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 122
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Abstract
Due to the increasing demand to generate thick and vascularized tissue-engineered constructs, novel strategies are currently being developed. An emerging example is the generation of oxygen-releasing biomaterials to tackle mass transport and diffusion limitations within engineered tissue constructs. Biomaterials containing oxygen-releasing molecules can be fabricated in various forms, such as hybrid thin films, microparticles or three dimensional scaffolds. In this perspective, we summarize various oxygen-releasing reagents and their potential applications in regenerative engineering. Moreover, we review the main approaches for fabricating oxygen-releasing biomaterials for a range of tissue engineering applications. © 2013 Society of Chemical Industry
组织工程用释氧生物材料
由于越来越多的需求产生厚和血管化的组织工程结构，新的策略目前正在开发。一个新兴的例子是产生释放氧气的生物材料，以解决工程组织结构中的质量传输和扩散限制。含有氧释放分子的生物材料可以制成各种形式，如杂交薄膜、微粒或三维支架。在这方面，我们总结了各种氧释放试剂及其在再生工程中的潜在应用。此外，我们回顾了制造氧释放生物材料的主要方法，用于一系列组织工程应用。©2013化工学会
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