Gross examination by the surgeon as an alternative to frozen section for assessment of adequacy of surgical margin in head and neck squamous cell carcinoma

IF 2.3 3区医学 Q1 OTORHINOLARYNGOLOGY

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2013-06-14 DOI:10.1002/hed.23313

Pankaj Chaturvedi MS, FAIS, FICS, MNAMS, FACS, Sourav Datta MS, Sudhir Nair MCh, Deepa Nair MS, Prashant Pawar MS, Sagar Vaishampayan MDS, Asawari Patil MD, Shubhada Kane MD

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引用次数: 25

Abstract

Background

The cost-effectiveness of the frozen section for assessment of margin in head and neck squamous cell carcinoma (HNSCC) is still contentious. The purpose of this study was to evaluate whether gross examination of margin is an alternative to frozen section.

Methods

It was a prospective observational study in 145 consecutive patients undergoing surgery for HNSCC. Surgical margins were first assessed by the surgeons with a metallic scale. All specimens were then examined using frozen section and permanent section.

Results

Overall, 83% of inadequate margins were detected by frozen section. The chances of inadequate margin were very low if gross surgical margin were 7 mm or more. Gross examination alone (with 7 mm as cutoff) predicted 88% of the inadequate surgical margin. There was no difference in precision of frozen section vis-à-vis gross examination with 7 mm cut off (p ≤ .8).

Conclusion

查看原文本刊更多论文

由外科医生进行大体检查，作为评估头颈部鳞状细胞癌手术切缘充分性的替代冷冻切片

背景冷冻切片评估头颈部鳞状细胞癌(HNSCC)边缘的成本效益仍有争议。本研究的目的是评估大体检查是否可以替代冷冻切片。方法对145例连续接受手术治疗的HNSCC患者进行前瞻性观察研究。外科医生首先用金属比例尺评估手术边缘。然后用冷冻切片和永久切片检查所有标本。结果总的来说，冷冻切片检出了83%的切缘不足。如果总手术切缘大于等于7毫米，切缘不充分的可能性非常低。单纯肉眼检查(以7mm为界限)预测88%的手术切缘不足。冷冻切片与-à-vis截7 mm肉眼检查精度无差异(p≤0.8)。结论外科医生测量的7 mm手术切缘可避免冷冻切片。©2013 Wiley期刊公司中国生物医学工程学报，2014,31 (6):557-563

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来源期刊

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 医学-耳鼻喉科学

CiteScore

7.00

自引率

6.90%

发文量

278

审稿时长

1.6 months

期刊介绍： Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.