[Idiopathic sudden deafness: a report of 96 patients].

F Gabanou, G Bera, C Vincent
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Abstract

Objectives: Evaluation of the management of idiopathic sudden deafness indicating the usefulness of biological assessments and the pronostic factors of hearing recovery.

Patients and methods: This is a retrospective study of 96 patients with idiopathic sudden deafness referred to a tertiary centre between 2005 and 2009 treated with corticosteroids intravenously at a daily dose of 1 mg/kg. Mean tonal thresholds were assessed (PTA = [500 Hz + 1000 Hz + 2000 Hz + 4000 Hz]/4). Each audiogram was classified as five classes according to its frequency profile.

Results: The hearing recovery is significant between D0-D5 and D5-M1 for the frequencies 0.5, 1 and 2 kHz. For 4 kHz, the recovery is significant between 0 and J5. There is no statistically significant correlation between the presence of associated signs (tinnitus, vertigo) and hearing recovery. Hearing recovery according to the five types of audiograms has the same evolution in the follow-up time but with audiograms type E (cophosis or subcophosis) often associated with an hyporeactivity at the videonystagmography. The presence of cardiovascular disease is a predictor of poor hearing recovery. The usefullness of systematic extensive blood tests is low.

Conclusion: In sudden deafness, the maximum hearing recovery takes place in the month following the onset of symptoms. The predictors of poor hearing recovery are an initial mean threshold > 70 dB, the existence of an associated cardiovascular disease.

特发性突发性耳聋96例报告
目的:评价特发性突发性耳聋的治疗方法,指出生物学评估的有效性和听力恢复的前驱因素。患者和方法:这是一项回顾性研究,在2005年至2009年期间,96例特发性突发性耳聋患者接受了皮质类固醇的静脉注射治疗,每日剂量为1mg /kg。评估平均音调阈值(PTA = [500 Hz + 1000 Hz + 2000 Hz + 4000 Hz]/4)。每个听力图根据其频率分布被分为五类。结果:D0-D5和D5-M1在0.5、1和2 kHz频率下听力恢复显著。对于4khz,在0和J5之间的恢复是显著的。相关症状(耳鸣、眩晕)与听力恢复之间无统计学意义的相关性。五种类型听音图的听力恢复在随访时间内具有相同的演变,但E型听音图(混音或亚混音)常伴有低反应性的视震图。心血管疾病的存在是听力恢复不良的一个预测因素。系统广泛的血液检查的有用性很低。结论:突发性耳聋在发病后一个月内听力恢复最快。听力恢复不良的预测指标是初始平均阈值> 70 dB,存在相关的心血管疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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