Andrea Spinelli, Bruna Vinci, Annalisa Tirella, Marco Matteucci, Luna Gargani, Arti Ahluwalia, Claudio Domenici, Eugenio Picano, Piero Chiarelli
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Abstract
In this work we describe the fabrication of a biocompatible hydrophilic scaffold composed of cross-linked gelatin that mimics the porous three-dimensional structure of pulmonary tissue as well as its water content and mechanical properties. The lung replica also reproduces the characteristic sonographic signs of pulmonary interstitial syndrome, the B-lines or ultrasound lung comets.
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