Maria Coutinho, Emília Costa, Tânia Monteiro, Gisela Silva, Helena Costa, Ana Guedes, Inês Freitas, José Barbot
{"title":"Infantile pyknocytosis: an under-recognized form of neonatal hemolytic anemia?","authors":"Maria Coutinho, Emília Costa, Tânia Monteiro, Gisela Silva, Helena Costa, Ana Guedes, Inês Freitas, José Barbot","doi":"10.1532/LH96.12005","DOIUrl":null,"url":null,"abstract":"<p><p>Infantile pyknocytosis (IP) is an under-recognized hematological entity of newborns that can cause a severe neonatal hemolytic anemia. A careful, prompt, and accurate peripheral blood smear examination is essential to establish the diagnosis. Here we describe the clinical features and histological parameters of 1 case of IP. Spontaneous resolution usually occurs by 4 to 6 months, but red blood cell transfusion may be needed if the anemia is severe.</p>","PeriodicalId":85078,"journal":{"name":"Laboratory hematology : official publication of the International Society for Laboratory Hematology","volume":"18 4","pages":"27-9"},"PeriodicalIF":0.0000,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Laboratory hematology : official publication of the International Society for Laboratory Hematology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1532/LH96.12005","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
Infantile pyknocytosis (IP) is an under-recognized hematological entity of newborns that can cause a severe neonatal hemolytic anemia. A careful, prompt, and accurate peripheral blood smear examination is essential to establish the diagnosis. Here we describe the clinical features and histological parameters of 1 case of IP. Spontaneous resolution usually occurs by 4 to 6 months, but red blood cell transfusion may be needed if the anemia is severe.