Engineering precise sequence-defined polymers for advanced functions

IF 26 1区 化学 Q1 POLYMER SCIENCE
Qiangqiang Shi , Zhengyu Deng , Mingxuan Hou , Xianglong Hu , Shiyong Liu
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引用次数: 4

Abstract

Unlike natural macromolecules (e.g., nucleic acids and proteins) possessing precisely defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically featured with broad chain length distributions, inhomogeneous compositions, and undefined sequences. To bridge the wide gap between natural and synthetic polymers, sequence-defined polymers (SDPs) have gradually emerged and developed with precise chain length, sequence, tacticity, and topology, holding great promise to reach the same level of precision, complexity, and functionality of biopolymers. The emergence of SDPs confers an unparalleled opportunity to precisely regulate their primary structures, rational intrachain and interchain self-organization, and macroscopic properties, enabling the fundamental elucidation of structure-function relationships. This review aims to summarize recent progresses in the synthesis and advanced applications of emerging and booming SDPs. Some prospects are proposed towards future challenges and versatile promising developments of SDPs.

Abstract Image

工程精确序列定义的聚合物先进的功能
与天然大分子(如核酸和蛋白质)具有精确定义的摩尔质量、链序列、手性和拓扑结构不同,合成聚合物通常具有宽链长分布、不均匀组成和未定义序列的特征。为了弥补天然聚合物和合成聚合物之间的巨大差距,序列定义聚合物(sdp)逐渐出现并发展起来,具有精确的链长,序列,弹性和拓扑结构,有望达到与生物聚合物相同的精度,复杂性和功能水平。sdp的出现为精确调节其初级结构、合理的链内和链间自组织以及宏观性质提供了前所未有的机会,从而从根本上阐明了结构-功能关系。本文综述了近年来新兴和蓬勃发展的sdp的合成和应用进展。对未来的挑战和sdp的广泛发展前景提出了展望。
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来源期刊
Progress in Polymer Science
Progress in Polymer Science 化学-高分子科学
CiteScore
48.70
自引率
1.10%
发文量
54
审稿时长
38 days
期刊介绍: Progress in Polymer Science is a journal that publishes state-of-the-art overview articles in the field of polymer science and engineering. These articles are written by internationally recognized authorities in the discipline, making it a valuable resource for staying up-to-date with the latest developments in this rapidly growing field. The journal serves as a link between original articles, innovations published in patents, and the most current knowledge of technology. It covers a wide range of topics within the traditional fields of polymer science, including chemistry, physics, and engineering involving polymers. Additionally, it explores interdisciplinary developing fields such as functional and specialty polymers, biomaterials, polymers in drug delivery, polymers in electronic applications, composites, conducting polymers, liquid crystalline materials, and the interphases between polymers and ceramics. The journal also highlights new fabrication techniques that are making significant contributions to the field. The subject areas covered by Progress in Polymer Science include biomaterials, materials chemistry, organic chemistry, polymers and plastics, surfaces, coatings and films, and nanotechnology. The journal is indexed and abstracted in various databases, including Materials Science Citation Index, Chemical Abstracts, Engineering Index, Current Contents, FIZ Karlsruhe, Scopus, and INSPEC.
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