Goiter and laryngopharyngeal reflux.

ISRN endocrinology Pub Date : 2012-01-01 Epub Date: 2012-03-05 DOI:10.5402/2012/208958
Abdul-Latif Hamdan, Jad Jabbour, Zaid Al Zaghal, Sami T Azar
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引用次数: 7

Abstract

The purpose of this study is to look at the prevalence of laryngopharyngeal reflux disease in patients with goiter in a group of 52 patients with goiter. All participants were asked to respond to the 9 questions on the Reflux Symptom Index (RSI). A diagnosis of LPRD based on symptoms was made for any RSI score above 10. The average score of every question was computed for all patients with goiter and compared to the corresponding average score of the controls. A P value of less than 0.05 was considered statistically significant. The total prevalence of LPRD in patients with goiter as indicated by an RSI score greater than 10 was 15.4% versus 9.1% in controls. The difference was not statistically significant (P value 0.525). Looking at the average score of the individual symptoms as listed in the RSI questionnaire, the average score of all the symptoms was higher in patients with goiter versus controls. There was no correlation between LPRD and any of the demographic variables except for nodules (P value 0.035). The presence of laryngopharyngeal symptoms in patients with goiter should alert the treating physician to the presence of laryngopharyngeal reflux disease.

甲状腺肿和咽喉反流。
本研究的目的是观察52例甲状腺肿患者中喉咽反流病的患病率。所有参与者都被要求回答关于反流症状指数(RSI)的9个问题。根据RSI评分高于10分的症状诊断LPRD。计算所有甲状腺肿患者每个问题的平均得分,并与对照组相应的平均得分进行比较。P值小于0.05认为有统计学意义。RSI评分大于10的甲状腺肿患者中LPRD的总患病率为15.4%,而对照组为9.1%。差异无统计学意义(P值0.525)。观察RSI问卷中列出的个体症状的平均得分,甲状腺肿患者的所有症状的平均得分高于对照组。除结节外,LPRD与其他人口统计学变量均无相关性(P值0.035)。甲状腺肿患者出现喉部症状时,应提醒主治医师注意喉部反流病的存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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