[Analysis of the genetic background and mechanisms of dissemination of resistance to tetracycline of the Polish population of Campylobacter strains isolated in Poland in years 2007-2008].

Tomasz Wołkowicz, Jolanta Szych, Sebastian Wardak
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Abstract

In Poland, constant rise of number of Campylobacter strains resistant to tetracycline is observed in Poland. Analysis of the resistant strains showed their strong diversity, including both the different levels of resistance to this drug, large differences in the sequence of the resistant gene tetO, and diverse phylogenetic origin. The study also confirmed the important role of horizontal spread of resistance which, in the event of such a large diversity of resistant strains, can cause further very rapid escalation of resistance of Campylobacter to tetracycline.

[2007-2008年波兰分离弯曲杆菌群体四环素耐药性遗传背景及传播机制分析]。
在波兰,观察到对四环素耐药的弯曲杆菌菌株数量不断上升。对耐药菌株的分析显示,耐药菌株具有很强的多样性,不仅对该药的耐药程度不同,而且耐药基因tetO序列差异较大,系统发育起源也存在差异。该研究还证实了耐药性水平传播的重要作用,在耐药菌株如此多样化的情况下,这种传播可能导致弯曲杆菌对四环素的耐药性进一步迅速升级。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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