{"title":"Novel Quantum Dots for Enhanced Tumor Imaging.","authors":"Ashwin Nair, Jinhui Shen, Paul Thevenot, Tong Cai, Zhibing Hu, Liping Tang","doi":"10.1109/NANO.2008.197","DOIUrl":null,"url":null,"abstract":"<p><p>So as to develop an effective tool for tumor imaging, we have embedded quantum dots (QD) in hydrogel nanoparticles. Their uptake in cancer cells has been studied in vitro and in a mice tumor model. Compared with QD alone, the QDs embedded in nanoparticles showed higher uptake in the tumor tissue. This novel conjugate can serve as a good imaging tool and also has the potential to serve as a carrier for drugs.</p>","PeriodicalId":89614,"journal":{"name":"Proceedings of the ... IEEE Conference on Nanotechnology. IEEE Conference on Nanotechnology","volume":"8 ","pages":"650-653"},"PeriodicalIF":0.0000,"publicationDate":"2008-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261784/pdf/nihms339294.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the ... IEEE Conference on Nanotechnology. IEEE Conference on Nanotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NANO.2008.197","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
So as to develop an effective tool for tumor imaging, we have embedded quantum dots (QD) in hydrogel nanoparticles. Their uptake in cancer cells has been studied in vitro and in a mice tumor model. Compared with QD alone, the QDs embedded in nanoparticles showed higher uptake in the tumor tissue. This novel conjugate can serve as a good imaging tool and also has the potential to serve as a carrier for drugs.