Alexander O. Brachmann , Ferdinand Kirchner , Carsten Kegler , Sebastian C. Kinski , Imke Schmitt , Helge B. Bode
{"title":"Triggering the production of the cryptic blue pigment indigoidine from Photorhabdus luminescens","authors":"Alexander O. Brachmann , Ferdinand Kirchner , Carsten Kegler , Sebastian C. Kinski , Imke Schmitt , Helge B. Bode","doi":"10.1016/j.jbiotec.2011.10.002","DOIUrl":null,"url":null,"abstract":"<div><p>The production of the blue pigment indigoidine has been achieved in the entomopathogenic bacterium <em>Photorhabdus luminescens</em> by a promoter exchange and in <em>Escherichia coli</em> following heterologous expression of the biosynthesis gene <em>indC</em>. Moreover, genes involved in the regulation of this previously “silent” biosynthesis gene cluster have been identified in <em>P. luminescens</em>.</p></div>","PeriodicalId":15153,"journal":{"name":"Journal of biotechnology","volume":null,"pages":null},"PeriodicalIF":4.1000,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jbiotec.2011.10.002","citationCount":"41","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biotechnology","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0168165611006079","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 41
Abstract
The production of the blue pigment indigoidine has been achieved in the entomopathogenic bacterium Photorhabdus luminescens by a promoter exchange and in Escherichia coli following heterologous expression of the biosynthesis gene indC. Moreover, genes involved in the regulation of this previously “silent” biosynthesis gene cluster have been identified in P. luminescens.
期刊介绍:
The Journal of Biotechnology has an open access mirror journal, the Journal of Biotechnology: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
The Journal provides a medium for the rapid publication of both full-length articles and short communications on novel and innovative aspects of biotechnology. The Journal will accept papers ranging from genetic or molecular biological positions to those covering biochemical, chemical or bioprocess engineering aspects as well as computer application of new software concepts, provided that in each case the material is directly relevant to biotechnological systems. Papers presenting information of a multidisciplinary nature that would not be suitable for publication in a journal devoted to a single discipline, are particularly welcome.