Autoimmune-mediated encephalitis.

IF 2.4 3区医学 Q2 CLINICAL NEUROLOGY

Neuroradiology Pub Date : 2011-11-01 Epub Date: 2011-01-27 DOI:10.1007/s00234-010-0832-0

Philippe Demaerel, Wim Van Dessel, Wim Van Paesschen, Rik Vandenberghe, Koen Van Laere, Jennifer Linn

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引用次数: 44

Abstract

Autoimmune-mediated encephalitis may occur as a paraneoplastic or as a non-paraneoplastic condition. The role of neuroimaging in autoimmune-mediated encephalitis has changed in the last decade partly due to improvements in sequence optimisation and higher field strength and partly due to the discovery of an increasing number of antibodies to neuronal cell and cell membrane antigens. Imaging is important since it can support the clinical diagnosis particularly in the absence of antibodies. Structural imaging findings can be subtle and are usually best seen on FLAIR images. A progressive as well as a relapsing-remitting course can be observed. Autoimmune-mediated encephalitis is classically linked to involvement of the hippocampus and amygdala, but extensive changes in the temporal cortex, basal ganglia, hypothalamus, brain stem, frontal and parietal cortex are not unusual. This report is based on a review of the literature (except the literature in Japanese) and own findings in patients with autoimmune-mediated encephalitis.

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谷蛋白脑炎。

自身免疫介导性脑炎可作为副肿瘤或非副肿瘤发生。神经成像在自身免疫介导的脑炎中的作用在过去十年中发生了变化，部分原因是序列优化的改进和更高的场强，部分原因是发现了越来越多的针对神经元细胞和细胞膜抗原的抗体。成像很重要，因为它可以支持临床诊断，特别是在没有抗体的情况下。结构成像结果可能很微妙，通常在FLAIR图像上最清晰。可以观察到进行性和复发缓解性病程。自身免疫介导的脑炎通常与海马和杏仁核受累有关，但颞叶皮层、基底神经节、下丘脑、脑干、额叶和顶叶皮层的广泛变化并不罕见。本报告基于文献综述(日语文献除外)和自身免疫介导性脑炎患者的发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuroradiology 医学-核医学

CiteScore

5.30

自引率

3.60%

发文量

214

审稿时长

4-8 weeks

期刊介绍： Neuroradiology aims to provide state-of-the-art medical and scientific information in the fields of Neuroradiology, Neurosciences, Neurology, Psychiatry, Neurosurgery, and related medical specialities. Neuroradiology as the official Journal of the European Society of Neuroradiology receives submissions from all parts of the world and publishes peer-reviewed original research, comprehensive reviews, educational papers, opinion papers, and short reports on exceptional clinical observations and new technical developments in the field of Neuroimaging and Neurointervention. The journal has subsections for Diagnostic and Interventional Neuroradiology, Advanced Neuroimaging, Paediatric Neuroradiology, Head-Neck-ENT Radiology, Spine Neuroradiology, and for submissions from Japan. Neuroradiology aims to provide new knowledge about and insights into the function and pathology of the human nervous system that may help to better diagnose and treat nervous system diseases. Neuroradiology is a member of the Committee on Publication Ethics (COPE) and follows the COPE core practices. Neuroradiology prefers articles that are free of bias, self-critical regarding limitations, transparent and clear in describing study participants, methods, and statistics, and short in presenting results. Before peer-review all submissions are automatically checked by iThenticate to assess for potential overlap in prior publication.