[Aortic dissection - a not so rare disease].

Medizinische Klinik Pub Date : 2010-12-01 Epub Date: 2011-01-16 DOI:10.1007/s00063-010-1151-2
Stefanie Jänisch, Nurzhan Turmanov, Urs-Vito Albrecht, Armin Fieguth, Detlef Günther
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引用次数: 2

Abstract

Background and purpose: Acute aortic dissection is a life-threatening disease with a high rate of mortality. The dissection of the artery with a distal blood flow can explain the variable and changeable symptoms. Aortic dissections require immediate diagnosis and therapy.

Methods: In the Institute of Legal Medicine of the Hannover Medical School, 34 cases of aortic dissection were found during autopsy between 2006 and 2009. The cases were analysed retrospectively.

Results: In the majority of cases (55.9%) an antemortem medical consultation has taken place. In only one case an aortic dissection could be diagnosed at a later time.

Conclusion: Key in the management of acute aortic dissection is to maintain a high clinical index of suspicion for this diagnosis. Etiologically hereditary diseases (Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome) should be taken into consideration as a possible cause. In all unexpected deaths of young adults an autopsy should be performed to detect the cause of death and for genetic testing to provide information for the relatives in case an aortic aneurysm can be found.

[主动脉夹层——一种不那么罕见的疾病]。
背景与目的:急性主动脉夹层是一种死亡率高、危及生命的疾病。有远端血流的动脉夹层可以解释这些变化无常的症状。主动脉夹层需要立即诊断和治疗。方法:对汉诺威医学院法医学研究所2006 ~ 2009年尸检中发现的主动脉夹层34例进行回顾性分析。对病例进行回顾性分析。结果:绝大多数病例(55.9%)曾进行过死前医学咨询。只有一例主动脉夹层可以在稍后的时间被诊断出来。结论:保持较高的临床怀疑指数是处理急性主动脉夹层的关键。病因学上的遗传性疾病(马凡氏综合征、埃勒斯-丹洛斯综合征、洛伊斯-迪茨综合征)应作为可能的病因加以考虑。在所有意外死亡的年轻人中,应进行尸检以查明死亡原因,并进行基因检测,以便在发现主动脉瘤的情况下为亲属提供信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medizinische Klinik
Medizinische Klinik 医学-医学:内科
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