Isolde Daig, Richard Mahlberg, Franziska Schroeder, Yehonala Gudlowski, Jana Wrase, Florian Wertenauer, Tom Bschor, Guenter Esser, Andreas Heinz, Thorsten Kienast
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引用次数: 14
Abstract
Objective: Alcohol-dependent patients in early abstinence show an impairment of cognitive functions which can be seen in poor implementation of newly learned skills for avoiding relapse. Executive dysfunction may persist during abstinence in alcohol-dependent persons, thus mitigating long-term abstinence. This study assessed visual memory function and choice of organizational strategies in alcoholics, as these are major factors necessary to implement ongoing behavior changes which are required for maintaining abstinence.
Methods: We investigated 25 severely alcohol-dependent male patients between days 7 to 10 of abstinence, immediately after clinical withdrawal symptoms have ceased, compared to 15 healthy age, sex, and education matched controls. Pharmacological therapy had been terminated at least four half-lifes before inclusion into the study. Visual perceptual learning and organizational strategies were assessed with the Rey-Osterrieth Complex Figure Test (R-OCF).
Results: There were no group differences in copying or recalling the figure, but time differences occurred. Alcoholics and healthy controls performed worse in recalling than in copying. But, alcoholics used less effective organizational strategies.
Conclusions: There was a deficit in choice of organizational strategy in newly abstinent and unmedicated alcohol-dependent patients. Due to the imperfect organizational strategies, alcoholics might need auxiliary therapeutic care to strengthen their cognitive ability.
目的:早期戒酒的酒精依赖患者表现出认知功能的损害,这可以从新学习的避免复发的技能执行不良中看出。在酒精依赖者戒酒期间,执行功能障碍可能持续存在,从而减轻长期戒酒。本研究评估了酗酒者的视觉记忆功能和组织策略选择,因为这些是实施持续行为改变所必需的主要因素,而行为改变是维持戒酒所必需的。方法:我们调查了25名严重酒精依赖的男性患者,在临床戒断症状停止后立即戒酒7至10天,与15名年龄、性别和教育程度匹配的健康对照组相比。在纳入研究之前,药物治疗至少已终止四个半衰期。采用Rey-Osterrieth Complex Figure Test (R-OCF)评估视觉知觉学习和组织策略。结果:组间在复制和回忆图形方面无差异,但存在时间差异。酗酒者和健康对照者在回忆方面的表现不如临摹。但是,酗酒者使用的组织策略不太有效。结论:新戒酒和未服药的酒精依赖患者在组织策略选择上存在缺陷。由于组织策略的不完善,酗酒者可能需要辅助的治疗护理来增强其认知能力。