Sören Laurisch, Maren Jaedtke, Reyhan Demir, Sajoscha A Sorrentino, Jan T Kielstein, Hans-Oliver Rennekampff, Peter M Vogt, Gerd P Meyer, Martin Fuchs, Gunnar Klein, Hartmut Drexler, Bernhard Schieffer, L Christian Napp
{"title":"[Allopurinol-induced hypersensitivity syndrome resulting in death].","authors":"Sören Laurisch, Maren Jaedtke, Reyhan Demir, Sajoscha A Sorrentino, Jan T Kielstein, Hans-Oliver Rennekampff, Peter M Vogt, Gerd P Meyer, Martin Fuchs, Gunnar Klein, Hartmut Drexler, Bernhard Schieffer, L Christian Napp","doi":"10.1007/s00063-010-1037-3","DOIUrl":null,"url":null,"abstract":"<p><p>The present report describes the case of a 67-year-old patient who developed an allopurinol-induced hypersensitivity syndrome (AHS) with toxic epidermal necrolysis and subsequently died of septic multiorgan failure. Considering the increasing prescription rate of allopurinol, the present case report intends to demonstrate the underestimated threat of AHS.</p>","PeriodicalId":18420,"journal":{"name":"Medizinische Klinik","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00063-010-1037-3","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medizinische Klinik","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00063-010-1037-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
The present report describes the case of a 67-year-old patient who developed an allopurinol-induced hypersensitivity syndrome (AHS) with toxic epidermal necrolysis and subsequently died of septic multiorgan failure. Considering the increasing prescription rate of allopurinol, the present case report intends to demonstrate the underestimated threat of AHS.